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Impact of beta-blockade premedication on image quality of ECG-gated thoracic aorta CT angiography.

dc.contributor.author Chalian, Hamid
dc.contributor.author Entezari, Pegah
dc.contributor.author Collins, Jeremy
dc.contributor.author Tore, Huseyin Gurkan
dc.contributor.author Carr, James
dc.contributor.author Yaghmai, Vahid
dc.date.accessioned 2019-04-02T17:58:27Z
dc.date.available 2019-04-02T17:58:27Z
dc.date.issued 2014-12
dc.identifier 0284185113516950
dc.identifier.issn 0284-1851
dc.identifier.issn 1600-0455
dc.identifier.uri https://hdl.handle.net/10161/18298
dc.description.abstract BACKGROUND: Thoracic aortic aneurysm is one of the most common aorta pathologies worldwide, which is commonly evaluated by computed tomography angiography (CTA). One of the routine methods to improve the image quality of CTA is heart rate reduction prior to study by beta-blockade administration. PURPOSE: To assess the effect of beta-blockade on image quality of the ascending aorta in electrocardiography (ECG)-gated dual-source CTA (DSCTA) images. MATERIAL AND METHODS: In this retrospective study, ECG-gated thoracic aorta CTA images of 40 patients without beta-blocker administration were compared with ECG-gated images of 40 patients with beta-blockade. Images of the aorta were analyzed objectively and subjectively at three levels: sinus of Valsalva (sinus), sinotubular junction (STJ), and mid ascending aorta (MAA). Quantitative sharpness index (SI) and signal-to-noise ratio (SNR) were calculated and two radiologists evaluated the image quality using a 3-point scale. RESULTS: Mean heart rate in beta-blocker and non-beta-blocker groups was 61.7 beats per minute (bpm) (range, 58.1-63.9 bpm) and 72.9 bpm (range, 69.3-84.1 bpm), respectively (P < 0.05). Aorta wall SI, SNR, and subjective grading were comparable between the two groups at all three levels (P > 0.05). CONCLUSION: Beta-blocker premedication may not be necessary for imaging of ascending aorta with ECG-gated DSCTA.
dc.language eng
dc.publisher SAGE Publications
dc.relation.ispartof Acta radiologica (Stockholm, Sweden : 1987)
dc.relation.isversionof 10.1177/0284185113516950
dc.subject Aorta, Thoracic
dc.subject Humans
dc.subject Aortic Aneurysm, Thoracic
dc.subject Adrenergic beta-Antagonists
dc.subject Radiographic Image Interpretation, Computer-Assisted
dc.subject Observer Variation
dc.subject Coronary Angiography
dc.subject Electrocardiography
dc.subject Premedication
dc.subject Retrospective Studies
dc.subject Middle Aged
dc.subject Female
dc.subject Male
dc.subject Cardiac-Gated Imaging Techniques
dc.title Impact of beta-blockade premedication on image quality of ECG-gated thoracic aorta CT angiography.
dc.type Journal article
dc.date.updated 2019-04-02T17:58:26Z
pubs.begin-page 1180
pubs.end-page 1185
pubs.issue 10
pubs.organisational-group School of Medicine
pubs.organisational-group Duke
pubs.organisational-group Radiology, Cardiothoracic Imaging
pubs.organisational-group Radiology
pubs.organisational-group Clinical Science Departments
pubs.publication-status Published
pubs.volume 55
duke.contributor.orcid Chalian, Hamid|0000-0001-8357-7347


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