Perioperative Management of Bleeding and Transfusion for Lung Transplantation.
Abstract
Perioperative allogeneic blood product transfusion is common in lung transplantation
and has various implications on the short- and long-term outcomes of lung recipients.
This review summarizes the effect of transfusion on outcomes including primary graft
dysfunction, chronic lung allograft dysfunction, and all-cause mortality. We outline
known risk factors for increased transfusion requirement in lung transplantation and
present current evidence regarding the effect of hemostatic agents including antifibrinolytics,
recombinant factor VII, and prothrombin complex concentrates. Finally, we highlight
the roles of point-of-care coagulation testing and goal-directed transfusion strategies
in reducing transfusion requirements in lung transplantation.
Type
Journal articleSubject
TACOTRALI
TRIM
chronic lung allograft dysfunction
lung transplantation
primary graft dysfunction
transfusion
Permalink
https://hdl.handle.net/10161/19283Published Version (Please cite this version)
10.1177/1089253219869030Publication Info
Pena, Joseph J; Bottiger, Brandi A; & Miltiades, Andrea N (2019). Perioperative Management of Bleeding and Transfusion for Lung Transplantation. Seminars in cardiothoracic and vascular anesthesia. pp. 1089253219869030. 10.1177/1089253219869030. Retrieved from https://hdl.handle.net/10161/19283.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
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Show full item recordScholars@Duke
Brandi Anne Bottiger
Associate Professor of Anesthesiology
I have been a member of the Cardiothoracic Anesthesiology division and Department
of anesthesiology for >10 years, caring for cardiac and thoracic surgical patients.
I am the current cardiothoracic anesthesiology fellowship director of 14 fellows (https://anesthesiology.duke.edu/?page_id=818051).
My academic interests are in education, CTA content development, and specific interests
in outcomes improvement after lung transplantation. Additionally, I have greatly appreciated
my leadershi

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