Clinical assessment and characterization of a dual tube kilovoltage X-ray localization system in the radiotherapy treatment room.
Abstract
INTRODUCTION:Although flat-panel based X-ray imaging has been well tested in diagnostic
radiology, its use as an image-guided-radiotherapy (IGRT) system in a treatment room
is new and requires systematic assessment. MATERIALS AND METHODS:BrainLab Novalis
IGRT system was used for this study. It consists of two floor mounted kV X-ray tubes
projecting obliquely into two flat-panel detectors mounted on the ceiling. The system
automatically fuses the 2D localization images with 3D simulation CT image to provide
positioning guidance. The following characteristics of the system were studied: (1)
Coincidence of the isocenters between the IGRT and Linac; (2) Image quality; (3) Exposure;
(4) Linearity, uniformity and repeatability. RESULTS:(1) Localization accuracy and
coincidence of the isocenters between the IGRT and Linac was better than 1-mm. (2)
The spatial resolution was quantified using the relative modulation-transfer-function
with f50=0.7-0.9 lp/mm. The variation of contrast-noise-ratio with technical settings
was measured. (3) The maximal exposure of an image was less than 95 mR. An empirical
relation between the exposure and the X-ray technical setting was derived. (4) The
linearity, uniformity and repeatability of the system generally meet the requirements.
CONCLUSION:The system can be safely and reliably used as a target localization device.
Type
Journal articleSubject
Radiographic Image Interpretation, Computer-AssistedTomography, X-Ray Computed
Radiotherapy, Conformal
Radiotherapy Dosage
Sensitivity and Specificity
Reproducibility of Results
Equipment Design
Equipment Failure Analysis
Radiometry
X-Ray Intensifying Screens
Permalink
https://hdl.handle.net/10161/19396Published Version (Please cite this version)
10.1120/jacmp.v9i1.2318Publication Info
Lee, Sung-Woo; Jin, Jian-Yue; Guan, Huaiqun; Martin, Flavious; Kim, Jae Ho; & Yin,
Fang-Fang (2008). Clinical assessment and characterization of a dual tube kilovoltage X-ray localization
system in the radiotherapy treatment room. Journal of applied clinical medical physics, 9(1). pp. 2318. 10.1120/jacmp.v9i1.2318. Retrieved from https://hdl.handle.net/10161/19396.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
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Show full item recordScholars@Duke
Fang-Fang Yin
Gustavo S. Montana Distinguished Professor of Radiation Oncology
Stereotactic radiosurgery, Stereotactic body radiation therapy, treatment planning
optimization, knowledge guided radiation therapy, intensity-modulated radiation therapy,
image-guided radiation therapy, oncological imaging and informatics

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