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Clinical assessment and characterization of a dual tube kilovoltage X-ray localization system in the radiotherapy treatment room.

dc.contributor.author Lee, Sung-Woo
dc.contributor.author Jin, Jian-Yue
dc.contributor.author Guan, Huaiqun
dc.contributor.author Martin, Flavious
dc.contributor.author Kim, Jae Ho
dc.contributor.author Yin, Fang-Fang
dc.date.accessioned 2019-10-04T15:50:43Z
dc.date.available 2019-10-04T15:50:43Z
dc.date.issued 2008-01-13
dc.identifier.issn 1526-9914
dc.identifier.issn 1526-9914
dc.identifier.uri https://hdl.handle.net/10161/19396
dc.description.abstract INTRODUCTION:Although flat-panel based X-ray imaging has been well tested in diagnostic radiology, its use as an image-guided-radiotherapy (IGRT) system in a treatment room is new and requires systematic assessment. MATERIALS AND METHODS:BrainLab Novalis IGRT system was used for this study. It consists of two floor mounted kV X-ray tubes projecting obliquely into two flat-panel detectors mounted on the ceiling. The system automatically fuses the 2D localization images with 3D simulation CT image to provide positioning guidance. The following characteristics of the system were studied: (1) Coincidence of the isocenters between the IGRT and Linac; (2) Image quality; (3) Exposure; (4) Linearity, uniformity and repeatability. RESULTS:(1) Localization accuracy and coincidence of the isocenters between the IGRT and Linac was better than 1-mm. (2) The spatial resolution was quantified using the relative modulation-transfer-function with f50=0.7-0.9 lp/mm. The variation of contrast-noise-ratio with technical settings was measured. (3) The maximal exposure of an image was less than 95 mR. An empirical relation between the exposure and the X-ray technical setting was derived. (4) The linearity, uniformity and repeatability of the system generally meet the requirements. CONCLUSION:The system can be safely and reliably used as a target localization device.
dc.language eng
dc.relation.ispartof Journal of applied clinical medical physics
dc.relation.isversionof 10.1120/jacmp.v9i1.2318
dc.subject Radiographic Image Interpretation, Computer-Assisted
dc.subject Tomography, X-Ray Computed
dc.subject Radiotherapy, Conformal
dc.subject Radiotherapy Dosage
dc.subject Sensitivity and Specificity
dc.subject Reproducibility of Results
dc.subject Equipment Design
dc.subject Equipment Failure Analysis
dc.subject Radiometry
dc.subject X-Ray Intensifying Screens
dc.title Clinical assessment and characterization of a dual tube kilovoltage X-ray localization system in the radiotherapy treatment room.
dc.type Journal article
duke.contributor.id Yin, Fang-Fang|0334491
dc.date.updated 2019-10-04T15:50:41Z
pubs.begin-page 2318
pubs.issue 1
pubs.organisational-group School of Medicine
pubs.organisational-group Duke
pubs.organisational-group Duke Kunshan University Faculty
pubs.organisational-group Duke Kunshan University
pubs.organisational-group Duke Cancer Institute
pubs.organisational-group Institutes and Centers
pubs.organisational-group Radiation Oncology
pubs.organisational-group Clinical Science Departments
pubs.publication-status Published
pubs.volume 9
duke.contributor.orcid Yin, Fang-Fang|0000-0002-2025-4740


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