Improved Dysphagia Outcomes in Anchored Spacers Versus Plate-Screw Systems in Anterior Cervical Discectomy and Fusion: A Systematic Review
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<jats:sec><jats:title>Study Design:</jats:title><jats:p> Systematic review and meta-analysis. </jats:p></jats:sec><jats:sec><jats:title>Objective:</jats:title><jats:p> To perform a systematic review of clinical outcomes between stand-alone anchored spacers and traditional cages with plate fixation for dysphagia and pseudoarthrosis using data from clinical trials. </jats:p></jats:sec><jats:sec><jats:title>Methods:</jats:title><jats:p> Our search protocol was added to PROSPERO register and systematic review using PRISMA method was performed. Then, we systematically searched for studies addressing stand-alone anchored spacers in patients who underwent ACDF. Mean Neck Disability Index (NDI), dysphagia incidence % (Dinc%), and Swallowing–Quality of Life (SQOL) scores during preoperative, immediate postoperative and last follow-up visits were extracted. Chi-square and analysis of variance (ANOVA) tests were used for statistical comparisons ( P ≤ .05). </jats:p></jats:sec><jats:sec><jats:title>Results:</jats:title><jats:p> The initial search generated 506 articles in CENTRAL and 40 articles in MEDLINE. Finally, 14 articles were included. Total number of patients was 1173 (583 anchored stand-alone and 590 plate). Dinc% scores were statistically significantly lower in the stand-alone anchored spacer compared to the plate-screw construct ( P ≤ .05). ANOVA showed no statistically significant difference in the comparisons of SQOL. On the other hand, NDI scores were statistically significantly lower in baseline of stand-alone anchored spacer and the plate-screw construct compared with both immediate postoperative and last follow-up visits ( P ≤ .05). </jats:p></jats:sec><jats:sec><jats:title>Conclusions:</jats:title><jats:p> Our study results revealed that the stand-alone anchored spacers were associated with less dysphagia in the immediate and last follow-up. </jats:p></jats:sec>
Published Version (Please cite this version)10.1177/2192568219895266
Publication InfoGabr, Mostafa A; Touko, Elisabeth; Yadav, Amol P; Karikari, Isaac; Goodwin, C Rory; Groff, Michael W; ... Abd-El-Barr, Muhammad M (n.d.). Improved Dysphagia Outcomes in Anchored Spacers Versus Plate-Screw Systems in Anterior Cervical Discectomy and Fusion: A Systematic Review. Global Spine Journal. pp. 219256821989526-219256821989526. 10.1177/2192568219895266. Retrieved from https://hdl.handle.net/10161/19776.
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Assistant Professor of Neurosurgery
As a Neurosurgeon with fellowship training in Spine Surgery, I have dedicated my professional life to treating patients with spine disorders. These include spinal stenosis, spondylolisthesis, scoliosis, herniated discs and spine tumors. I incorporate minimally-invasive spine (MIS) techniques whenever appropriate to minimize pain and length of stay, yet not compromise on achieving the goals of surgery, which is ultimately to get you back to the quality of life you once enjoyed. I was drawn to med
Research Associate, Senior
Dr. Gabr's research has specifically focused on the following broad areas: (i) animal model of myelopathy, (ii) participating in clinical trials in spine field.In the last few years, this research agenda has expanded to include collaborative projects and publications. Dr. Gabr and his colleagues explore benefit of cervical collar following spine fusion, spinal cord injury model, and transforaminal lumbar interbody fusion.Dr. Gabr is the author of "Interleukin-17 synergizes with IFNI&
Assistant Professor of Neurosurgery
Associate Professor of Neurosurgery
Dr. Yadav is a neuroscientist and biomedical engineer, currently a postdoctoral associate in the Department of Neurosurgery where he collaborates with neurosurgeons on translational neuroscience research.
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