Association Between Substance Use and Gun-Related Behaviors.
Abstract
Gun-related violence is a public health concern. This study synthesizes findings on
associations between substance use and gun-related behaviors. Searches through PubMed,
Embase, and PsycINFO located 66 studies published in English between 1992 and 2014.
Most studies found a significant bivariate association between substance use and increased
odds of gun-related behaviors. However, their association after adjustment was mixed,
which could be attributed to a number of factors such as variations in definitions
of substance use and gun activity, study design, sample demographics, and the specific
covariates considered. Fewer studies identified a significant association between
substance use and gun access/possession than other gun activities. The significant
association between nonsubstance covariates (e.g., demographic covariates and other
behavioral risk factors) and gun-related behaviors might have moderated the association
between substance use and gun activities. Particularly, the strength of association
between substance use and gun activities tended to reduce appreciably or to become
nonsignificant after adjustment for mental disorders. Some studies indicated a positive
association between the frequency of substance use and the odds of engaging in gun-related
behaviors. Overall, the results suggest a need to consider substance use in research
and prevention programs for gun-related violence.
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Journal articlePermalink
https://hdl.handle.net/10161/19946Published Version (Please cite this version)
10.1093/epirev/mxv013Publication Info
Chen, Danhong; & Wu, Li-Tzy (2016). Association Between Substance Use and Gun-Related Behaviors. Epidemiologic reviews, 38(1). pp. 46-61. 10.1093/epirev/mxv013. Retrieved from https://hdl.handle.net/10161/19946.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
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Show full item recordScholars@Duke
Li-Tzy Wu
Professor in Psychiatry and Behavioral Sciences
Education/Training: Pre- and post-doctoral training in mental health service research,
psychiatric epidemiology (NIMH T32), and addiction epidemiology (NIDA T32) from Johns
Hopkins University School of Public Health (Maryland); Fellow of the NIH Summer Institute
on the Design and Conduct of Randomized Clinical Trials.Director: Duke Community Based
Substance Use Disorder Research Program.Research interests: COVID-19, Opioid misuse,
Opioid overdose, Opioid use disorder

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