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An item response theory analysis of DSM-IV criteria for hallucinogen abuse and dependence in adolescents.
Abstract
AIM:This study applied both item response theory (IRT) and multiple indicators-multiple
causes (MIMIC) methods to evaluate item-level psychometric properties of diagnostic
questions for hallucinogen use disorders (HUDs), differential item functioning (DIF),
and predictors of latent HUD. METHODS:Data were drawn from 2004-2006 National Surveys
on Drug Use and Health. Analyses were based on 1548 past-year hallucinogen users aged
12-17 years. Substance use and symptoms were assessed by audio computer-assisted self-interviewing
methods. RESULTS:Abuse and dependence criteria empirically were arrayed along a single
continuum of severity. All abuse criteria indicated middle-to-high severity on the
IRT-defined HUD continuum, while dependence criteria captured a wider range from the
lowest (tolerance and time spent) to the highest (taking larger amounts and inability
to cut down) severity levels. There was indication of DIF by hallucinogen users' age,
gender, race/ethnicity, and ecstasy use status. Adjusting for DIF, ecstasy users (vs.
non-ecstasy hallucinogen users), females (vs. males), and whites (vs. Hispanics) exhibited
increased odds of HUD. CONCLUSIONS:Symptoms of hallucinogen abuse and dependence empirically
do not reflect two discrete conditions in adolescents. Trends and problems related
to hallucinogen use among girls and whites should be examined further to inform the
designs of effective gender-appropriate and culturally sensitive prevention programs.
Type
Journal articleSubject
HumansSubstance-Related Disorders
Hallucinogens
Risk Factors
Self Disclosure
Psychometrics
Age Factors
Sex Factors
Diagnostic and Statistical Manual of Mental Disorders
Adolescent
Child
Ethnic Groups
Female
Male
Surveys and Questionnaires
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https://hdl.handle.net/10161/19998Published Version (Please cite this version)
10.1016/j.addbeh.2009.10.009Publication Info
Wu, Li-Tzy; Pan, Jeng-Jong; Yang, Chongming; Reeve, Bryce B; & Blazer, Dan G (2010). An item response theory analysis of DSM-IV criteria for hallucinogen abuse and dependence
in adolescents. Addictive behaviors, 35(3). pp. 273-277. 10.1016/j.addbeh.2009.10.009. Retrieved from https://hdl.handle.net/10161/19998.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
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Show full item recordScholars@Duke
Daniel German Blazer
J. P. Gibbons Distinguished Professor Emeritus of Psychiatry
I am currently semi-retired. Most of my recent work has been focused on roles with
the National Academy of Medicine (former Institute of Medicine). I have chaired three
committees during the past four years, one on the mental health and substance use workforce,
one on cognitive aging, and one on hearing loss in adults. I currently also chair
the Board on the Health of Select Populations for the National Academies. In the past
I have been PI on a number of research
Bryce B. Reeve
Professor in Population Health Sciences
Dr. Bryce Reeve is a Professor of Population Health Sciences and Professor of Pediatrics
at Duke University School of Medicine. He also serves as Director of the Center for
Health Measurement since 2017. Trained in psychometric methods, Dr. Reeve’s work
focuses on assessing the impact of disease and treatments on the lives of patients
and their caregivers. This includes the development of clinical outcome assessments
using both qualitative and quantitative methods, and
Li-Tzy Wu
Professor in Psychiatry and Behavioral Sciences
Education/Training: Pre- and post-doctoral training in mental health service research,
psychiatric epidemiology (NIMH T32), and addiction epidemiology (NIDA T32) from Johns
Hopkins University School of Public Health (Maryland); Fellow of the NIH Summer Institute
on the Design and Conduct of Randomized Clinical Trials.Director: Duke Community Based
Substance Use Disorder Research Program.Research interests: COVID-19, Opioid misuse,
Opioid overdose, Opioid use disorder
Alphabetical list of authors with Scholars@Duke profiles.

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