The Project Baseline Health Study: a step towards a broader mission to map human health.
Abstract
The Project Baseline Health Study (PBHS) was launched to map human health through
a comprehensive understanding of both the health of an individual and how it relates
to the broader population. The study will contribute to the creation of a biomedical
information system that accounts for the highly complex interplay of biological, behavioral,
environmental, and social systems. The PBHS is a prospective, multicenter, longitudinal
cohort study that aims to enroll thousands of participants with diverse backgrounds
who are representative of the entire health spectrum. Enrolled participants will be
evaluated serially using clinical, molecular, imaging, sensor, self-reported, behavioral,
psychological, environmental, and other health-related measurements. An initial deeply
phenotyped cohort will inform the development of a large, expanded virtual cohort.
The PBHS will contribute to precision health and medicine by integrating state of
the art testing, longitudinal monitoring and participant engagement, and by contributing
to the development of an improved platform for data sharing and analysis.
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https://hdl.handle.net/10161/21114Published Version (Please cite this version)
10.1038/s41746-020-0290-yPublication Info
(2020). The Project Baseline Health Study: a step towards a broader mission to map human health.
NPJ digital medicine, 3(1). pp. 84. 10.1038/s41746-020-0290-y. Retrieved from https://hdl.handle.net/10161/21114.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
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Mustafa Shadi Rifaat Bashir
Associate Professor of Radiology
Hepatobiliary and pancreatic imagingLiver cancer (hepatocellular carcinoma)Fatty liver,
NAFLD, and NASHChronic liver disease and cirrhosisPancreatic cancerTechnical development
in MRIQuantitative imaging
Pamela Susan Douglas
Ursula Geller Distinguished Professor for Research in Cardiovascular Disease, in the
School of Medicine
Pamela S Douglas MD is the Ursula Geller Professor of Research in Cardiovascular Diseases
in the Department of Medicine at Duke University and Director of the Multimodality
Imaging Program at Duke Clinical Research Institute. During her 30+ years of experience
she has led several landmark multicenter government studies and pivotal industry clinical
trials along with outcomes research studies. She is renowned for her scientific and
policy work in improving the quality and appropriateness
Geoffrey Steven Ginsburg
Adjunct Professor in the Department of Medicine
Dr. Geoffrey S. Ginsburg's research interests are in the development of novel paradigms
for developing and translating genomic information into medical practice and the integration
of personalized medicine into health care.
Adrian Felipe Hernandez
Duke Health Cardiology Professor
Erich Senin Huang
Assistant Professor in Biostatistics and Bioinformatics
Chief Data Officer for Quality, Duke HealthDirector of Duke ForgeDirector of Duke
CrucibleAssistant Dean for Biomedical InformaticsDr. Huang’s research interests span
applied machine learning, research provenance and data infrastructure. Projects include
building data provenance tools funded by the NIH’s Big Data to Knowledge program,
regulatory science funded by the Burroughs Wellcom
Shannon Jones McCall
Associate Professor of Pathology
As Vice Chair for Translational Research in the Department of Pathology, I am involved
in numerous translational cancer research projects that rely on the study of human
biological samples. I am the director of the Duke BioRepository & Precision Pathology
Center (Duke BRPC), a shared resource of the School of Medicine and the Duke Cancer
Institute. I serve as the PI for the National Cancer Institute's Cooperative Human
Tissue Network Southern Division (a five-year UM1 grant), whi
Lawrence H. Muhlbaier
Associate Professor Emeritus of Biostatistics & Bioinformatics
HIPAA and other regulatory systems and their impact on Research
Patient Privacy
Evaluation of outcomes in cardiac surgical patients.
Validate statistical models of short and long term outcome of patients with IHD in
non-academic databases.
Developing methods to present these evaluations so that they can be incorporated into
patient care activities on an ongoing basis.
To understand the variability in the utilization of medical care serv
Laura Kristin Newby
Professor of Medicine
Research Description General Focus: Clinical investigation the process and treatment
of acute and chronic coronary artery disease and systems issues for delivery of care
to patients with these illnesses. Particular interests include management of patients
with chest pain and unstable angina, evaluation of the use of biochemical markers
other than CK-MB for diagnosis and risk stratification in these patients, issues related
to coronary artery disease in women, and systems issues
Michael J Pencina
Professor of Biostatistics & Bioinformatics
As Vice Dean for Data Science, Dr. Pencina is responsible for developing and implementing
quantitative science strategies as they pertain to the education and training, and
laboratory, clinical science, and data science missions of the School of Medicine.
Dr. Pencina is a Professor of Biostatistics and Bioinformatics at Duke University
and Director of Duke AI Health. Previously, he served as Director of Biostatistics
at the Duke Clinical Research Institute.
Dr. Pencina is an internati
Eric David Peterson
Fred Cobb, M.D. Distinguished Professor of Medicine
Dr Peterson is the Fred Cobb Distinguished Professor of Medicine in the Division of
Cardiology, a DukeMed Scholar, and the Past Executive Director of the Duke Clinical
Research Institute (DCRI), Durham, NC, USA.
Dr Peterson is the Principal Investigator of the National Institute of Health, Lung
and Blood Institute (NHLBI) Spironolactone Initiation Registry Randomized Interventional
Trial in Heart Failure With Preserved Ejection Fraction (SPIRRIT) Trial He is also
the Principal I
This author no longer has a Scholars@Duke profile, so the information shown here reflects
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Svati Hasmukh Shah
Professor of Medicine
Geeta Krishna Swamy
Professor of Obstetrics and Gynecology
Dr. Geeta Swamy, MD, is Professor of Obstetrics and Gynecology in the Division of
Maternal-Fetal Medicine, having served as the director of the Duke Perinatal Research
Center and Vice Chair for Research and Faculty Development in the Department of ObGyn.
She has achieved international acclaim as a clinician researcher and expert in the
field of maternal immunization and perinatal infection. As a consultant to the World
Health Organization, Dr. Swamy contributes her knowledge to advance inte
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