Using weighted power mean for equivalent square estimation.
Abstract
Equivalent Square (ES) enables the calculation of many radiation quantities for rectangular
treatment fields, based only on measurements from square fields. While it is widely
applied in radiotherapy, its accuracy, especially for extremely elongated fields,
still leaves room for improvement. In this study, we introduce a novel explicit ES
formula based on Weighted Power Mean (WPM) function and compare its performance with
the Sterling formula and Vadash/Bjärngard's formula.The proposed WPM formula is ESWPMa,b=waα+1-wbα1/α
for a rectangular photon field with sides a and b. The formula performance was evaluated
by three methods: standard deviation of model fitting residual error, maximum relative
model prediction error, and model's Akaike Information Criterion (AIC). Testing datasets
included the ES table from British Journal of Radiology (BJR), photon output factors
(Scp ) from the Varian TrueBeam Representative Beam Data (Med Phys. 2012;39:6981-7018),
and published Scp data for Varian TrueBeam Edge (J Appl Clin Med Phys. 2015;16:125-148).For
the BJR dataset, the best-fit parameter value α = -1.25 achieved a 20% reduction in
standard deviation in ES estimation residual error compared with the two established
formulae. For the two Varian datasets, employing WPM reduced the maximum relative
error from 3.5% (Sterling) or 2% (Vadash/Bjärngard) to 0.7% for open field sizes ranging
from 3 cm to 40 cm, and the reduction was even more prominent for 1 cm field sizes
on Edge (J Appl Clin Med Phys. 2015;16:125-148). The AIC value of the WPM formula
was consistently lower than its counterparts from the traditional formulae on photon
output factors, most prominent on very elongated small fields.The WPM formula outperformed
the traditional formulae on three testing datasets. With increasing utilization of
very elongated, small rectangular fields in modern radiotherapy, improved photon output
factor estimation is expected by adopting the WPM formula in treatment planning and
secondary MU check.
Type
Journal articleSubject
HumansNeoplasms
Radiotherapy Dosage
Radiotherapy Planning, Computer-Assisted
Data Collection
Radiology
Photons
Particle Accelerators
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https://hdl.handle.net/10161/21117Published Version (Please cite this version)
10.1002/acm2.12201Publication Info
Zhou, Sumin; Wu, Qiuwen; Li, Xiaobo; Ma, Rongtao; Zheng, Dandan; Wang, Shuo; ... Enke,
Charles (2017). Using weighted power mean for equivalent square estimation. Journal of applied clinical medical physics, 18(6). pp. 194-199. 10.1002/acm2.12201. Retrieved from https://hdl.handle.net/10161/21117.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
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Show full item recordScholars@Duke
Qiuwen Wu
Professor of Radiation Oncology
My research interests include intensity-modulated radiation therapy (IMRT), volumetric
modulated arc therapy (VMAT), electron arc therapy (EAT) and image-guided radiation
therapy (IGRT). For IMRT, my work include the development of the research platform,
fast and accurate dose calculations, optimization based on physical and biological
objectives such as generalized equivalent uniform dose (gEUD), and delivery with dynamic
multi-leaf collimator (DMLC). For VMAT, I am interested in the optim

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