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Constraint and trade-offs regulate energy expenditure during childhood.

dc.contributor.author Urlacher, Samuel S
dc.contributor.author Snodgrass, J Josh
dc.contributor.author Dugas, Lara R
dc.contributor.author Sugiyama, Lawrence S
dc.contributor.author Liebert, Melissa A
dc.contributor.author Joyce, Cara J
dc.contributor.author Pontzer, Herman
dc.date.accessioned 2020-07-01T16:01:40Z
dc.date.available 2020-07-01T16:01:40Z
dc.date.issued 2019-12-18
dc.identifier aax1065
dc.identifier.issn 2375-2548
dc.identifier.issn 2375-2548
dc.identifier.uri https://hdl.handle.net/10161/21130
dc.description.abstract Children's metabolic energy expenditure is central to evolutionary and epidemiological frameworks for understanding variation in human phenotype and health. Nonetheless, the impact of a physically active lifestyle and heavy burden of infectious disease on child metabolism remains unclear. Using energetic, activity, and biomarker measures, we show that Shuar forager-horticulturalist children of Amazonian Ecuador are ~25% more physically active and, in association with immune activity, have ~20% greater resting energy expenditure than children from industrial populations. Despite these differences, Shuar children's total daily energy expenditure, measured using doubly labeled water, is indistinguishable from industrialized counterparts. Trade-offs in energy allocation between competing physiological tasks, within a constrained energy budget, appear to shape childhood phenotypic variation (e.g., patterns of growth). These trade-offs may contribute to the lifetime obesity and metabolic health disparities that emerge during rapid economic development.
dc.language eng
dc.publisher American Association for the Advancement of Science (AAAS)
dc.relation.ispartof Science advances
dc.relation.isversionof 10.1126/sciadv.aax1065
dc.subject Humans
dc.subject Exercise
dc.subject Life Style
dc.subject Age Factors
dc.subject Energy Metabolism
dc.subject Child
dc.subject Female
dc.subject Male
dc.subject Public Health Surveillance
dc.subject Biomarkers
dc.title Constraint and trade-offs regulate energy expenditure during childhood.
dc.type Journal article
duke.contributor.id Pontzer, Herman|0903448
dc.date.updated 2020-07-01T16:01:39Z
pubs.begin-page eaax1065
pubs.issue 12
pubs.organisational-group Trinity College of Arts & Sciences
pubs.organisational-group Evolutionary Anthropology
pubs.organisational-group Duke Global Health Institute
pubs.organisational-group Duke
pubs.organisational-group University Institutes and Centers
pubs.organisational-group Institutes and Provost's Academic Units
pubs.publication-status Published
pubs.volume 5


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