Hospital mortality of patients aged 80 and older after surgical repair for type A acute aortic dissection in Japan.
Abstract
To evaluate whether patients aged 80 and older have higher risk of hospital mortality
after repair of type A acute aortic dissection (TAAAD).Emergency surgery for TAAAD
in patients aged 80 and older remains a controversial issue because of its high surgical
risk.Data from patients who underwent surgical repair of TAAAD between April 2011
and March 2013 were retrospectively extracted from the Japanese Diagnosis Procedure
Combination database. The effect of age on hospital mortality was evaluated using
multivariate logistic regression analysis.A total of 5175 patients were enrolled.
The mean age of patients was 67.1 ± 13.0 years, and the male:female ratio was 51:49.
Patients aged 80 and older more frequently received tracheostomy than their younger
counterparts (9.5% vs 5.4%, P <0.001). Intensive care unit and hospital stays were
significantly longer in the elderly cohort versus the younger cohort (7.6 vs 6.7 days,
P <0.001, and 42.2 vs 35.8 days, P <0.001, respectively). Logistic regression analysis
showed that age ≥80 years was significantly associated with a higher risk of hospital
mortality (adjusted odds ratio, 1.62; 95% confidence interval, 1.28-2.06; P <0.001).
In linear regression analysis, age ≥80 years was also significantly associated with
longer hospital stay (P = 0.007).In a large, nationwide, Japanese database, patients
aged 80 and older were at increased risk of hospital mortality and length of hospital
stay.
Type
Journal articleSubject
HumansAneurysm, Dissecting
Aortic Aneurysm, Thoracic
Length of Stay
Cause of Death
Hospital Mortality
Linear Models
Risk Assessment
Retrospective Studies
Age Factors
Databases, Factual
Aged
Aged, 80 and over
Middle Aged
Japan
Female
Male
Permalink
https://hdl.handle.net/10161/21338Published Version (Please cite this version)
10.1097/md.0000000000004408Publication Info
Ohnuma, Tetsu; Shinjo, Daisuke; & Fushimi, Kiyohide (2016). Hospital mortality of patients aged 80 and older after surgical repair for type A
acute aortic dissection in Japan. Medicine, 95(31). pp. e4408. 10.1097/md.0000000000004408. Retrieved from https://hdl.handle.net/10161/21338.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
Collections
More Info
Show full item recordScholars@Duke
Tetsu Ohnuma
Assistant Professor in Anesthesiology

Articles written by Duke faculty are made available through the campus open access policy. For more information see: Duke Open Access Policy
Rights for Collection: Scholarly Articles
Works are deposited here by their authors, and represent their research and opinions, not that of Duke University. Some materials and descriptions may include offensive content. More info