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Factors predicting successful discontinuation of continuous renal replacement therapy.

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Date
2016-07
Authors
Katayama, S
Uchino, S
Uji, M
Ohnuma, T
Namba, Y
Kawarazaki, H
Toki, N
Takeda, K
Yasuda, H
Izawa, J
Tokuhira, N
Nagata, I
Japanese Society of Education for Physicians and Trainees in Intensive Care (JSEPTIC) Clinical Trial Group
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Abstract
This multicentre, retrospective observational study was conducted from January 2010 to December 2010 to determine the optimal time for discontinuing continuous renal replacement therapy (CRRT) by evaluating factors predictive of successful discontinuation in patients with acute kidney injury. Analysis was performed for patients after CRRT was discontinued because of renal function recovery. Patients were divided into two groups according to the success or failure of CRRT discontinuation. In multivariate logistic regression analysis, urine output at discontinuation, creatinine level and CRRT duration were found to be significant variables (area under the receiver operating characteristic curve for urine output, 0.814). In conclusion, we found that higher urine output, lower creatinine and shorter CRRT duration were significant factors to predict successful discontinuation of CRRT.
Type
Journal article
Subject
Japanese Society of Education for Physicians and Trainees in Intensive Care (JSEPTIC) Clinical Trial Group
Humans
Creatinine
Renal Replacement Therapy
Logistic Models
Retrospective Studies
Time Factors
Aged
Middle Aged
Female
Male
Acute Kidney Injury
Permalink
https://hdl.handle.net/10161/21340
Published Version (Please cite this version)
10.1177/0310057x1604400401
Publication Info
Katayama, S; Uchino, S; Uji, M; Ohnuma, T; Namba, Y; Kawarazaki, H; ... Japanese Society of Education for Physicians and Trainees in Intensive Care (JSEPTIC) Clinical Trial Group (2016). Factors predicting successful discontinuation of continuous renal replacement therapy. Anaesthesia and intensive care, 44(4). pp. 453-457. 10.1177/0310057x1604400401. Retrieved from https://hdl.handle.net/10161/21340.
This is constructed from limited available data and may be imprecise. To cite this article, please review & use the official citation provided by the journal.
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Scholars@Duke

Ohnuma

Tetsu Ohnuma

Assistant Professor in Anesthesiology
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