Factors predicting successful discontinuation of continuous renal replacement therapy.
Abstract
This multicentre, retrospective observational study was conducted from January 2010
to December 2010 to determine the optimal time for discontinuing continuous renal
replacement therapy (CRRT) by evaluating factors predictive of successful discontinuation
in patients with acute kidney injury. Analysis was performed for patients after CRRT
was discontinued because of renal function recovery. Patients were divided into two
groups according to the success or failure of CRRT discontinuation. In multivariate
logistic regression analysis, urine output at discontinuation, creatinine level and
CRRT duration were found to be significant variables (area under the receiver operating
characteristic curve for urine output, 0.814). In conclusion, we found that higher
urine output, lower creatinine and shorter CRRT duration were significant factors
to predict successful discontinuation of CRRT.
Type
Journal articleSubject
Japanese Society of Education for Physicians and Trainees in Intensive Care (JSEPTIC)
Clinical Trial GroupHumans
Creatinine
Renal Replacement Therapy
Logistic Models
Retrospective Studies
Time Factors
Aged
Middle Aged
Female
Male
Acute Kidney Injury
Permalink
https://hdl.handle.net/10161/21340Published Version (Please cite this version)
10.1177/0310057x1604400401Publication Info
Katayama, S; Uchino, S; Uji, M; Ohnuma, T; Namba, Y; Kawarazaki, H; ... Japanese Society
of Education for Physicians and Trainees in Intensive Care (JSEPTIC) Clinical Trial
Group (2016). Factors predicting successful discontinuation of continuous renal replacement therapy.
Anaesthesia and intensive care, 44(4). pp. 453-457. 10.1177/0310057x1604400401. Retrieved from https://hdl.handle.net/10161/21340.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
Collections
More Info
Show full item recordScholars@Duke
Tetsu Ohnuma
Assistant Professor in Anesthesiology

Articles written by Duke faculty are made available through the campus open access policy. For more information see: Duke Open Access Policy
Rights for Collection: Scholarly Articles
Works are deposited here by their authors, and represent their research and opinions, not that of Duke University. Some materials and descriptions may include offensive content. More info