Generating evidence for therapeutic effects: the need for well-conducted randomized trials.
Abstract
In this viewpoint, Robert Califf, former commissioner of the U.S. Food and Drug Administration,
and colleagues reflect on how to approach questions about which patient treatments
and strategies work, particularly in light of the tremendous pressure on the government
and biomedical research enterprise to quickly develop safe, effective therapies during
the SARS-CoV-2 pandemic.
Type
Journal articlePermalink
https://hdl.handle.net/10161/22009Published Version (Please cite this version)
10.1172/jci146391Publication Info
Califf, Robert M; Curtis, Lesley H; Harrington, Robert A; Hernandez, Adrian F; & Peterson,
Eric D (2020). Generating evidence for therapeutic effects: the need for well-conducted randomized
trials. The Journal of clinical investigation. 10.1172/jci146391. Retrieved from https://hdl.handle.net/10161/22009.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
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Show full item recordScholars@Duke
Lesley H. Curtis
Professor in Population Health Sciences
Lesley H. Curtis is Professor in the Departments of Population Health Sciences and
Medicine in the Duke School of Medicine and was inaugural chair of the Department
of Population Health Sciences. A health services researcher by training, Dr. Curtis
is an expert in the use of health care and Medicare claims data for health services
and clinical outcomes research, and a leader in national data quality efforts. Dr.
Curtis has led the linkage of Medicare claims with seve
Adrian Felipe Hernandez
Duke Health Cardiology Professor
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