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Normative dataset for plasma cytokines in healthy human adults.

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Date
2021-04
Authors
Li, Yingkai
Yi, John S
Russo, Melissa A
Rosa-Bray, Marilyn
Weinhold, Kent J
Guptill, Jeffrey T
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Abstract
We determined normative data for plasma cytokines established from a cohort of 126 carefully screened healthy adults aged 18 to 64 years. Participants were enrolled to ensure an even age and sex distribution and to include at least 30% non-Caucasians. Plasma cytokines for 18 analytes were tested by multiplex immunoassay. The data are presented by age cohort (18-29 years, 30-39, 40-49, and 50-66), as well as by sex and racial background. This dataset complements published normative ranges of cellular subsets generated by comprehensive polychromatic flow cytometry analysis of the healthy human immune system [1]. These data are available to researchers and have value as a reference range for research involving peripheral cytokines.
Type
Journal article
Subject
Cytokines
Healthy volunteer
Normative range
Reference range
Reference value
Permalink
https://hdl.handle.net/10161/22466
Published Version (Please cite this version)
10.1016/j.dib.2021.106857
Publication Info
Li, Yingkai; Yi, John S; Russo, Melissa A; Rosa-Bray, Marilyn; Weinhold, Kent J; & Guptill, Jeffrey T (2021). Normative dataset for plasma cytokines in healthy human adults. Data in brief, 35. pp. 106857. 10.1016/j.dib.2021.106857. Retrieved from https://hdl.handle.net/10161/22466.
This is constructed from limited available data and may be imprecise. To cite this article, please review & use the official citation provided by the journal.
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Scholars@Duke

Guptill

Jeffrey Guptill

Adjunct Associate Professor in the Department of Neurology
Weinhold

Kent James Weinhold

Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery
In addition to their ongoing HIV/AIDS-related research activities, the Weinhold Laboratory is focused on utilizing a comprehensive repertoire of highly standardized and formerly validated assay platforms to profile the human immune system in order to identify immunologic signatures that predict disease outcomes. These ongoing studies span a broad range of highly relevant clinical arenas, including: 1) cancer (non-small cell lung cancer, head and neck cancer, glioblastoma neof
Yi

John S Yi

Adjunct Assistant Professor in the Department of Surgery
I am an immunologist, with a focus to characterize the immune system in response to infectious and non-infectious diseases including cancer, HIV, autoimmune disease, and transplantation. My goals are to identify novel biomarkers/immune signatures that clinicians can utilize to diagnosis, predict disease outcomes, and determine patients' response to treatment. 
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