Activation of Rod Input in a Model of Retinal Degeneration Reverses Retinal Remodeling and Induces Formation of Functional Synapses and Recovery of Visual Signaling in the Adult Retina.
Retinal Bipolar Cells
Cyclic Nucleotide-Gated Cation Channels
Retinal Rod Photoreceptor Cells
Photoreceptor Cells, Vertebrate
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Retinal Ganglion Cells With a Glaucoma OPTN(E50K) Mutation Exhibit Neurodegenerative Phenotypes when Derived from Three-Dimensional Retinal Organoids. VanderWall, Kirstin B; Huang, Kang-Chieh; Pan, Yanling; Lavekar, Sailee S; Fligor, Clarisse M; Allsop, Anna R; Lentsch, Kelly A; ... (12 authors) (Stem cell reports, 2020-07)Retinal ganglion cells (RGCs) serve as the connection between the eye and the brain, with this connection disrupted in glaucoma. Numerous cellular mechanisms have been associated with glaucomatous neurodegeneration, and ...
Auditory and olfactory findings in patients with USH2A-related retinal degeneration-Findings at baseline from the rate of progression in USH2A-related retinal degeneration natural history study (RUSH2A). Iannaccone, Alessandro; Brewer, Carmen C; Cheng, Peiyao; Duncan, Jacque L; Maguire, Maureen G; Audo, Isabelle; Ayala, Allison R; ... (17 authors) (American journal of medical genetics. Part A, 2021-07-30)Sensorineural hearing loss (SNHL) is characteristic of Usher syndrome type 2 (USH2), but less is known about SNHL in nonsyndromic autosomal recessive retinitis pigmentosa (ARRP) and olfaction in USH2A-associated retinal ...
Mac Grory, Brian; Landman, Sean R; Ziegler, Paul D; Boisvert, Chantal J; Flood, Shane P; Stretz, Christoph; Madsen, Tracy E; ... (20 authors)<jats:sec> <jats:title>Background:</jats:title> <jats:p>Central retinal artery occlusion (CRAO) causes sudden, irreversible blindness and is a form of acute ischemic stroke. In this study, we sought ...