Short-Term Trajectories of Depressive Symptoms in Stroke Survivors and Their Family Caregivers.
Abstract
<h4>Goal</h4>We utilize group-based trajectory modeling (GBTM) to delineate depressive
symptom trajectories among stroke survivor-caregiver dyads, to identify predictors
of the delineated trajectories, and to assess the influence of time-varying covariates
(stroke survivor depressive symptoms and functional disability, caregiver depressive
symptoms, and foreign domestic worker [FDW] assistance) on the level of the depressive
symptom trajectories.<h4>Methods</h4>Data on 172 stroke survivor-caregiver dyads in
Singapore, for whom depressive symptoms were assessed thrice (baseline/3 months/6
months), were utilized. GBTM was applied to delineate depressive symptom trajectories,
and to identify their predictors and time-varying covariates.<h4>Findings</h4>Three
stroke survivor depressive symptom trajectories (low and decreasing [47.6%], low and
increasing [43.1%], and high and increasing [9.3%]) and 2 caregiver depressive symptom
trajectories (low and stable [71.5%] and high and decreasing [28.5%]) were delineated.
Caregivers with chronic diseases were more likely (odds ratio [95% confidence interval]:
8.09[2.04-32.07]) and those caring for older stroke survivors (0.94[0.90-0.98]) were
less likely to follow the high and decreasing than the low and stable depressive symptom
trajectory. An increase in stroke survivor functional disability and caregiver depressive
symptoms led to a rise (~worsening) in stroke survivor depressive symptom trajectories.
Whereas an increase in stroke survivor depressive symptoms led to a rise in caregiver
depressive symptom trajectories, FDW assistance led to a decline (~improvement).<h4>Conclusion</h4>Care
professionals should be mindful of heterogeneity in depressive symptom patterns over
time among stroke survivor-caregiver dyads. Reciprocal association of depressive symptoms
in the stroke survivor-caregiver dyad suggests that addressing mood problems in 1
member may benefit the other member, and calls for dyadic mental health interventions.
Type
Journal articleSubject
HumansDisease Progression
Disability Evaluation
Severity of Illness Index
Follow-Up Studies
Depression
Models, Psychological
Socioeconomic Factors
Aged
Aged, 80 and over
Middle Aged
Caregivers
Survivors
Singapore
Female
Male
Stroke
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https://hdl.handle.net/10161/22821Published Version (Please cite this version)
10.1016/j.jstrokecerebrovasdis.2015.09.012Publication Info
Malhotra, Rahul; Chei, Choy-Lye; Menon, Edward; Chow, Wai Leng; Quah, Stella; Chan,
Angelique; & Matchar, David Bruce (2016). Short-Term Trajectories of Depressive Symptoms in Stroke Survivors and Their Family
Caregivers. Journal of stroke and cerebrovascular diseases : the official journal of National
Stroke Association, 25(1). pp. 172-181. 10.1016/j.jstrokecerebrovasdis.2015.09.012. Retrieved from https://hdl.handle.net/10161/22821.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
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Show full item recordScholars@Duke
David Bruce Matchar
Professor of Medicine
My research relates to clinical practice improvement - from the development of clinical
policies to their implementation in real world clinical settings. Most recently my
major content focus has been cerebrovascular disease. Other major clinical areas in
which I work include the range of disabling neurological conditions, cardiovascular
disease, and cancer prevention. Notable features of my work are: (1) reliance on
analytic strategies such as meta-analysis, simulation, decision analy

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