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<p>Background: There is a rising burden of myocardial infarction (MI) within sub-Saharan
Africa. Prospective studies of detailed MI outcomes in the region are lacking. </p><p>Methods:Adult
patients with confirmed MI from a prospective surveillance study in northern Tanzania
were enrolled in a longitudinal cohort study after baseline health history, medication
use, barriers to care, and sociodemographics were obtained. Thirty days following
hospital presentation, symptom status, rehospitalizations, medication use, and mortality
were assessed via telephone or in-person interviews using a standardized follow-up
questionnaire. Multivariate logistic regression was performed to identify baseline
predictors of thirty-day survival.</p><p>Results:Thirty-day follow-up was achieved
for 150 (98.7%) of 152 enrolled participants. Of these, 85 (56·7%) survived to thirty-day
follow-up. Of the surviving participants, 71 (83·5%) reported persistent anginal symptoms,
four (4·7%) reported taking aspirin regularly, seven (8·2%) were able to identify
MI as the reason for their hospitalization, and 17 (20·0%) had unscheduled rehospitalizations.
Baseline predictors of thirty-day survival included self-reported history of diabetes
(OR 0·32, 95% CI 0·10-0·89, p = 0·04), self-reported history of hypertension (OR 0·34,
95% CI 0·15-0·74, p = 0·01) and antiplatelet use at initial presentation (OR 0·19,
95% CI 0·04-0·65, p = 0·02).</p><p>Conclusions:In northern Tanzania, thirty-day outcomes
following acute MI are poor, and mortality is associated with comorbidities and medication
usage. Further investigation is needed to develop interventions to improve care and
outcomes of MI in Tanzania.
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