Validation of the Finnish Version of the Unified Dyskinesia Rating Scale.
Abstract
<h4>Introduction</h4>The Unified Dyskinesia Rating Scale (UDysRS) was developed to
provide a comprehensive rating tool of dyskinesia in Parkinson's disease (PD). Because
dyskinesia therapy trials involve multicenter studies, having a scale that is validated
in multiple non-English languages is pivotal to international efforts to treat dyskinesia.
The aim of the present study was to organize and perform an independent validation
of the UDysRS Finnish version.<h4>Methods</h4>The UDysRS was translated into Finnish
and then back-translated into English using 2 independent teams. Cognitive pretesting
was conducted on the Finnish version and required modifications to the structure or
wording of the translation. The final Finnish version was administered to 250 PD patients
whose native language is Finnish. The data were analyzed to assess the confirmatory
factor structure to the Spanish UDysRS (the reference standard). Secondary analyses
included an exploratory factor analysis (EFA), independent of the reference standard.<h4>Results</h4>The
comparative fit index (CFI), in comparison with the reference standard factor structure,
was 0.963 for Finnish. In the EFA, where variability from sample to sample is expected,
isolated item differences of factor structure were found between the Finnish and Reference
Standard versions of the UDysRS. These subtle differences may relate to differences
in sample composition or variations in disease status.<h4>Conclusion</h4>The overall
factor structure of the Finnish version was consistent with that of the reference
standard, and it can be designated as the official version of the UDysRS for Finnish
speaking populations.
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https://hdl.handle.net/10161/23472Published Version (Please cite this version)
10.1159/000517369Publication Info
Kaasinen, Valtteri; Scheperjans, Filip; Kärppä, Mikko; Korpela, Jaana; Brück, Anna;
Sipilä, Jussi OT; ... Pekkonen, Eero (2021). Validation of the Finnish Version of the Unified Dyskinesia Rating Scale. European neurology. pp. 1-6. 10.1159/000517369. Retrieved from https://hdl.handle.net/10161/23472.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
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Sheng Luo
Professor of Biostatistics & Bioinformatics

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