Pilot Cohorts for Development of Concurrent Mobile Treatment for Alcohol and Tobacco Use Disorders.
Abstract
Alcohol and tobacco are the 2 most frequently used drugs in the United States and
represent the highest co-occurrence of polysubstance use. The objective of this study
was to refine an intervention combining mobile contingency management with cognitive-behavioral
telephone counseling for concurrent treatment of alcohol and tobacco use disorders.
Two cohorts (n = 13 total, n = 5 women) of participants were enrolled, with 10/13
completing treatment and 7/13 completing the 6-month follow-up. At enrollment, participants
were drinking a mean of 28.9 drinks per week (SD = 14.1), with a mean of 14.7 heavy
drinking days in the past month (SD = 9.9), and a mean of 18.1 cigarettes per day
(SD = 11.7). Treatment included a mobile application that participants used to record
carbon monoxide and breath alcohol content readings to bioverify abstinence. Participants
received up to 4 sessions of phone cognitive-behavioral therapy and monetary reinforcement
contingent on abstinence. In cohort 1, 4/6 participants reported abstinent or low-risk
drinking post-monitoring. Six weeks post quit-date, 2/6 participants were CO-bioverified
abstinent from tobacco use, with 2/6 in dual remission. These results were maintained
at 6-months. In cohort 2, 6/7 reported abstinent or low-risk drinking post-monitoring,
5 weeks post quit-date. At the post-monitoring visit, 5/7 were CO-bioverified abstinent
from smoking, with 5/7 in dual remission. At 6-months, 3/7 reporting abstinent or
low-risk drinking, 1/7 had bioverified abstinence from smoking, with 1/7 in dual remission.
Observations suggest that it is possible to develop a concurrent mobile treatment
for alcohol and tobacco use disorders.
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https://hdl.handle.net/10161/23862Published Version (Please cite this version)
10.1177/11782218211030524Publication Info
Medenblik, Alyssa M; Calhoun, Patrick S; Maisto, Stephen A; Kivlahan, Daniel R; Moore,
Scott D; Beckham, Jean C; ... Dedert, Eric A (2021). Pilot Cohorts for Development of Concurrent Mobile Treatment for Alcohol and Tobacco
Use Disorders. Substance abuse : research and treatment, 15. pp. 11782218211030524. 10.1177/11782218211030524. Retrieved from https://hdl.handle.net/10161/23862.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
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Show full item recordScholars@Duke
Jean Crowell Beckham
Professor in Psychiatry and Behavioral Sciences
Interest in assessment and treatment of trauma, particularly as occurs for both women
and men during military service; focus in treatment outcome of differential and collective
contribution for psychopharmacological and behavioral interventions in PTSD populations;
long term physical health effects of chronic posttraumatic stress disorder.
Daniel Blalock
Assistant Consulting Professor in the Department of Psychiatry and Behavioral Sciences
I am a behavioral health researcher with a background in Clinical Psychology and Experimental
Psychology. My research interests include broad processes of behavior change and
self-regulation as well as psychometric measurement and research methods/statistics.
My specific research endeavors include 1) the measurement and behavior change applicability
of constructs related to self-control, 2) measurement and interventions to improve
self-regulatory health behaviors including medication
Patrick Shields Calhoun
Professor in Psychiatry and Behavioral Sciences
I specialize in the assessment and treatment of the psychological and behavioral sequelae
of posttraumatic stress disorder (PTSD) including the use of cognitive-behavioral
interventions to reduce PTSD symptoms, aggression, and substance misuse.
Research interests
The psychological, behavioral, and health consequences of traumatic stress
Health services research related to PTSD and associated behavioral difficulties
Identification of innova
Eric Dedert
Associate Professor in Psychiatry and Behavioral Sciences
I am a Research Psychologist at the Durham VA Medical Center and Associate Professor
at the Duke University Medical Center, where I conduct research with the Traumatic
Stress and Health Research Laboratory. I am currently leading an trial on the clinical
and cost effectiveness of mobile contingency management as an adjunct to evidence-based
cognitive behavioral therapy for Veterans with alcohol use disorder. I am also leading
a trial of concurrent evidence-based treatments of posttraumatic stres
Scott Daniel Moore
Professor of Psychiatry and Behavioral Sciences
We are currently developing a model system for the investigation of physiological
effects of acute ethanol. This model utilizes a rat brain slice preparation incorporating
the amygdala, a brain region associated with anxiety and ethanol-induced anxiolysis.
We anticipate expanding this model to investigate effects of other anxiolytic agents
and to elucidate the basic mechanisms underlying anxiogenesis. We are also currently
examining the neurobiological basis of seizure-induced
Sarah M Wilson
Assistant Professor in Psychiatry and Behavioral Sciences
Sarah M. Wilson is an Assistant Professor in the Department of Psychiatry & Behavioral
Sciences at the Duke University School of Medicine, with a secondary appointment in
the Department of Population Health Sciences and a faculty affiliation in the Duke
Center for Health Policy and Inequalities Research. She is a Research Investigator
and Co-Lead of the Diversity, Equity, and Inclusion Core at the Veterans Affairs Center
of Innovation to Accelerate Discovery and Practice Transformation (ADAP
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