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Pilot Cohorts for Development of Concurrent Mobile Treatment for Alcohol and Tobacco Use Disorders.

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Date
2021-01
Authors
Medenblik, Alyssa M
Calhoun, Patrick S
Maisto, Stephen A
Kivlahan, Daniel R
Moore, Scott D
Beckham, Jean C
Wilson, Sarah M
Blalock, Dan V
Dedert, Eric A
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Abstract
Alcohol and tobacco are the 2 most frequently used drugs in the United States and represent the highest co-occurrence of polysubstance use. The objective of this study was to refine an intervention combining mobile contingency management with cognitive-behavioral telephone counseling for concurrent treatment of alcohol and tobacco use disorders. Two cohorts (n = 13 total, n = 5 women) of participants were enrolled, with 10/13 completing treatment and 7/13 completing the 6-month follow-up. At enrollment, participants were drinking a mean of 28.9 drinks per week (SD = 14.1), with a mean of 14.7 heavy drinking days in the past month (SD = 9.9), and a mean of 18.1 cigarettes per day (SD = 11.7). Treatment included a mobile application that participants used to record carbon monoxide and breath alcohol content readings to bioverify abstinence. Participants received up to 4 sessions of phone cognitive-behavioral therapy and monetary reinforcement contingent on abstinence. In cohort 1, 4/6 participants reported abstinent or low-risk drinking post-monitoring. Six weeks post quit-date, 2/6 participants were CO-bioverified abstinent from tobacco use, with 2/6 in dual remission. These results were maintained at 6-months. In cohort 2, 6/7 reported abstinent or low-risk drinking post-monitoring, 5 weeks post quit-date. At the post-monitoring visit, 5/7 were CO-bioverified abstinent from smoking, with 5/7 in dual remission. At 6-months, 3/7 reporting abstinent or low-risk drinking, 1/7 had bioverified abstinence from smoking, with 1/7 in dual remission. Observations suggest that it is possible to develop a concurrent mobile treatment for alcohol and tobacco use disorders.
Type
Journal article
Subject
Alcohol
cognitive behavioral therapy
comorbidity
contingency management
tobacco
Permalink
https://hdl.handle.net/10161/23862
Published Version (Please cite this version)
10.1177/11782218211030524
Publication Info
Medenblik, Alyssa M; Calhoun, Patrick S; Maisto, Stephen A; Kivlahan, Daniel R; Moore, Scott D; Beckham, Jean C; ... Dedert, Eric A (2021). Pilot Cohorts for Development of Concurrent Mobile Treatment for Alcohol and Tobacco Use Disorders. Substance abuse : research and treatment, 15. pp. 11782218211030524. 10.1177/11782218211030524. Retrieved from https://hdl.handle.net/10161/23862.
This is constructed from limited available data and may be imprecise. To cite this article, please review & use the official citation provided by the journal.
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Scholars@Duke

Beckham

Jean Crowell Beckham

Professor in Psychiatry and Behavioral Sciences
Interest in assessment and treatment of trauma, particularly as occurs for both women and men during military service; focus in treatment outcome of differential and collective contribution for psychopharmacological and behavioral interventions in PTSD populations; long term physical health effects of chronic posttraumatic stress disorder.
Blalock

Daniel Blalock

Assistant Consulting Professor in the Department of Psychiatry and Behavioral Sciences
I am a behavioral health researcher with a background in Clinical Psychology and Experimental Psychology.  My research interests include broad processes of behavior change and self-regulation as well as psychometric measurement and research methods/statistics.  My specific research endeavors include 1) the measurement and behavior change applicability of constructs related to self-control, 2) measurement and interventions to improve self-regulatory health behaviors including medication
Calhoun

Patrick Shields Calhoun

Professor in Psychiatry and Behavioral Sciences
I specialize in the assessment and treatment of the psychological and behavioral sequelae of posttraumatic stress disorder (PTSD) including the use of cognitive-behavioral interventions to reduce PTSD symptoms, aggression, and substance misuse.  Research interests The psychological, behavioral, and health consequences of traumatic stress Health services research related to PTSD and associated behavioral difficulties Identification of innova
Dedert

Eric Dedert

Associate Professor in Psychiatry and Behavioral Sciences
I am a Research Psychologist at the Durham VA Medical Center and Associate Professor at the Duke University Medical Center, where I conduct research with the Traumatic Stress and Health Research Laboratory. I am currently leading an trial on the clinical and cost effectiveness of mobile contingency management as an adjunct to evidence-based cognitive behavioral therapy for Veterans with alcohol use disorder. I am also leading a trial of concurrent evidence-based treatments of posttraumatic stres
Moore

Scott Daniel Moore

Professor of Psychiatry and Behavioral Sciences
We are currently developing a model system for the investigation of physiological effects of acute ethanol. This model utilizes a rat brain slice preparation incorporating the amygdala, a brain region associated with anxiety and ethanol-induced anxiolysis. We anticipate expanding this model to investigate effects of other anxiolytic agents and to elucidate the basic mechanisms underlying anxiogenesis. We are also currently examining the neurobiological basis of seizure-induced

Sarah M Wilson

Assistant Professor in Psychiatry and Behavioral Sciences
Sarah M. Wilson is an Assistant Professor in the Department of Psychiatry & Behavioral Sciences at the Duke University School of Medicine, with a secondary appointment in the Department of Population Health Sciences and a faculty affiliation in the Duke Center for Health Policy and Inequalities Research. She is a Research Investigator and Co-Lead of the Diversity, Equity, and Inclusion Core at the Veterans Affairs Center of Innovation to Accelerate Discovery and Practice Transformation (ADAP
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