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Massively parallel quantification of phenotypic heterogeneity in single-cell drug responses.

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Date
2021-09-17
Authors
Yellen, Benjamin B
Zawistowski, Jon S
Czech, Eric A
Sanford, Caleb I
SoRelle, Elliott D
Luftig, Micah A
Forbes, Zachary G
Wood, Kris C
Hammerbacher, Jeff
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Abstract
[Figure: see text].
Type
Journal article
Permalink
https://hdl.handle.net/10161/23877
Published Version (Please cite this version)
10.1126/sciadv.abf9840
Publication Info
Yellen, Benjamin B; Zawistowski, Jon S; Czech, Eric A; Sanford, Caleb I; SoRelle, Elliott D; Luftig, Micah A; ... Hammerbacher, Jeff (2021). Massively parallel quantification of phenotypic heterogeneity in single-cell drug responses. Sci Adv, 7(38). pp. eabf9840. 10.1126/sciadv.abf9840. Retrieved from https://hdl.handle.net/10161/23877.
This is constructed from limited available data and may be imprecise. To cite this article, please review & use the official citation provided by the journal.
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Scholars@Duke

Luftig

Micah Alan Luftig

Professor of Molecular Genetics and Microbiology
The Luftig laboratory studies viruses that cause cancer with an overarching goal of defining the basic molecular mechanisms underlying pathogenesis and leveraging these findings for diagnostic value and therapeutic intervention. Our work primarily focuses on the common herpesvirus, Epstein-Barr virus (EBV). This virus latently infects virtually all adults worldwide being acquired early in life. In the immune suppressed, EBV promotes lymphomas in the B cells that it naturally infects. However, EB
Sorelle

Elliott Sorelle

Postdoctoral Associate
Wood

Kris Cameron Wood

Associate Professor of Pharmacology and Cancer Biology
Our laboratory uses genomic and pharmacological approaches to understand how tumor dependencies are shaped by cell intrinsic factors, environmental factors, and drug treatments during the dynamic process of tumor evolution. To learn more, please visit our laboratory website: https://woodlabduke.com/.
Yellen

Benjamin Yellen

Associate Professor in the Department of Mechanical Engineering and Materials Science
Yellen's group is interested in developing highly parallel mechanisms for controlling the transport and assembly of ensembles of objects ranging from micron-sized colloidal particles to single cells.  As of 2013, Professor Yellen is active in two main areas of research:1) Development of single cell analysis tools using magnetic circuits. The goal of this project is to develop an automated single cell analysis platform that allows for highly flexible and highly paralle
Alphabetical list of authors with Scholars@Duke profiles.
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