Amilorides inhibit SARS-CoV-2 replication in vitro by targeting RNA structures
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https://hdl.handle.net/10161/24025Published Version (Please cite this version)
10.1126/sciadv.abl6096Publication Info
(2021). Amilorides inhibit SARS-CoV-2 replication in vitro by targeting RNA structures. Science Advances, 7(48). 10.1126/sciadv.abl6096. Retrieved from https://hdl.handle.net/10161/24025.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
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Show full item recordScholars@Duke
Amanda Hargrove
Associate Professor of Chemistry
The Hargrove lab harnesses the unique properties of small organic molecules to study
the structure, function and therapeutic potential of long noncoding RNAs (lncRNAs).
The discovery of these fascinating biomolecules has caused a paradigm shift in molecular
biology and speculation as to their role as the master drivers of diseases such as
cancer. At the same time very little is known about their structure and function,
leading some to call the field a veritable “wild West.” Small molecules are t
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