Perception of Stigma and Its Associated Factors Among Patients With Major Depressive Disorder: A Multicenter Survey From an Asian Population.
Abstract
Stigma of major depressive disorder (MDD) is an important public health problem. This
study aimed to examine the level of perceived stigma and its associated factors in
MDD patients in five Asian countries, including China, Korea, Malaysia, Singapore,
and Thailand. A total of 547 outpatients with MDD were included from Asian countries.
We used the stigma scale of the Explanatory Model Interview Catalogue (EMIC) to assess
stigma. The Montgomery-Asberg Depression Rating Scale (MADRS), Symptoms Checklist
90-Revised (SCL-90-R), Fatigue Severity Scale (FSS), Sheehan Disability Scale (SDS),
36-Item Short-Form Health Survey (SF-36), and Multidimensional Scale of Perceived
Social Support (MSPSS) were used to assess symptoms, clinical features, functional
impairment, health status, and social support. The stigma scores of patients under
55 years old were significantly higher than those equal to or greater than 55 years
old (P < 0.001). The stigma scores exhibited significant negative correlation with age;
MSPSS scores of family, friends, and others; and SF-36 subscale of mental health,
but significant positive correlation with MADRS, FSS, SDS, and SCL-90-R subscale scores
of depression, interpersonal sensitivity, obsession-compulsion, psychoticism, and
somatization. Multivariate regression analysis revealed that age, SCL-90-R interpersonal
sensitivity, obsession-compulsion, psychoticism, MSPSS scores of friends and others,
and SF-36 of mental health were significantly associated with the level of perceived
stigma. These findings suggest that MDD patients who are young, have a high degree
of interpersonal sensitivity and psychoticism, have low health-related quality of
life, and have low social support are the target population for stigma interventions
in Asia.
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https://hdl.handle.net/10161/24815Published Version (Please cite this version)
10.3389/fpsyt.2019.00321Publication Info
Sun, Yan; Chen, Gang; Wang, Li; Li, Nan; Srisurapanont, Manit; Hong, Jin Pyo; ...
Si, Tian-Mei (2019). Perception of Stigma and Its Associated Factors Among Patients With Major Depressive
Disorder: A Multicenter Survey From an Asian Population. Frontiers in psychiatry, 10(MAY). pp. 321. 10.3389/fpsyt.2019.00321. Retrieved from https://hdl.handle.net/10161/24815.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
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Augustus John Rush
Adjunct Professor in the Department of Psychiatry and Behavioral Sciences

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