Mullerian agenesis associated with in-utero thalidomide exposure: A case report
Abstract
Thalidomide is a well-known teratogen, which is experiencing resurgence as new uses
are identified. Exposure is classically associated with limb deformities, such as:
dysmelia, phocomelia, preaxial hypoplasia and polydactyly, in addition to visceral
anomalies that have been documented as well. We report a case of a 38 year-old nulligravid
female, who was previously evaluated for primary amenorrhea, and given the presumptive
false diagnosis of an imperforate hymen. On magnetic resonance imaging (MRI) exam,
she was noted to have uterovaginal agenesis. The implications of thalidomide on women's
health extend beyond external birth defects. Although, most commonly associated with
limb deformities, there may also be gynecologic implications of in utero exposure.
As this medication is increasingly used for various medical conditions, obstetricians/gynecologists
need to remain aware of this potential mullerian teratogenic effect. © 2013 Production
and hosting by Elsevier B.V. on behalf of Middle East Fertility Society.
Type
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https://hdl.handle.net/10161/25033Published Version (Please cite this version)
10.1016/j.mefs.2013.01.007Publication Info
Dotters-Katz, S; Muasher, LC; & Muasher, SJ (2013). Mullerian agenesis associated with in-utero thalidomide exposure: A case report. Middle East Fertility Society Journal, 18(3). pp. 214-216. 10.1016/j.mefs.2013.01.007. Retrieved from https://hdl.handle.net/10161/25033.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
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Show full item recordScholars@Duke
Sarah K. Dotters-Katz
Associate Professor of Obstetrics and Gynecology
My passion is for medical education. As a resident, I was recognized for excellence
in teaching by the medical students during all four years of my training, and completed
the “Resident as Teacher” program during that time as well. I have obtained
my Masters of Medical Health Professions Education from Eastern Virginia Medical School
from 2016-2017. During that time, I also completed the University of North Carolina
Faculty Scholars program and was inducted into the University of
Lisa Coates Muasher
Assistant Professor of Obstetrics and Gynecology
Suheil Jamil Muasher
Professor Emeritus of Obstetrics and Gynecology
I currently hold the position of Director of Graduate Learning and Academic Development.
I am responsible for the education of the second year residents rotating in REI and
director of second year medical student rotation in REI. I give ten resident lectures
per year covering all the CREOG educational requirements. I also conduct case based
learning sessions for the medical students throughout the year (2 hours per week).
I conduct journal club sessions with t
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