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Mullerian agenesis associated with in-utero thalidomide exposure: A case report

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Date
2013-09-01
Authors
Dotters-Katz, S
Muasher, LC
Muasher, SJ
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Abstract
Thalidomide is a well-known teratogen, which is experiencing resurgence as new uses are identified. Exposure is classically associated with limb deformities, such as: dysmelia, phocomelia, preaxial hypoplasia and polydactyly, in addition to visceral anomalies that have been documented as well. We report a case of a 38 year-old nulligravid female, who was previously evaluated for primary amenorrhea, and given the presumptive false diagnosis of an imperforate hymen. On magnetic resonance imaging (MRI) exam, she was noted to have uterovaginal agenesis. The implications of thalidomide on women's health extend beyond external birth defects. Although, most commonly associated with limb deformities, there may also be gynecologic implications of in utero exposure. As this medication is increasingly used for various medical conditions, obstetricians/gynecologists need to remain aware of this potential mullerian teratogenic effect. © 2013 Production and hosting by Elsevier B.V. on behalf of Middle East Fertility Society.
Type
Journal article
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https://hdl.handle.net/10161/25033
Published Version (Please cite this version)
10.1016/j.mefs.2013.01.007
Publication Info
Dotters-Katz, S; Muasher, LC; & Muasher, SJ (2013). Mullerian agenesis associated with in-utero thalidomide exposure: A case report. Middle East Fertility Society Journal, 18(3). pp. 214-216. 10.1016/j.mefs.2013.01.007. Retrieved from https://hdl.handle.net/10161/25033.
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Scholars@Duke

Dotters-Katz

Sarah K. Dotters-Katz

Associate Professor of Obstetrics and Gynecology
My passion is for medical education. As a resident, I was recognized for excellence in teaching by the medical students during all four years of my training, and completed the “Resident as Teacher” program during that time as well. I have obtained my Masters of Medical Health Professions Education from Eastern Virginia Medical School from 2016-2017. During that time, I also completed the University of North Carolina Faculty Scholars program and was inducted into the University of
Muasher

Lisa Coates Muasher

Assistant Professor of Obstetrics and Gynecology
Muasher

Suheil Jamil Muasher

Professor Emeritus of Obstetrics and Gynecology
I currently hold the position of Director of Graduate Learning and Academic Development.  I am responsible for the education of the second year residents rotating in REI and director of second year medical student rotation in REI.  I give ten resident lectures per year covering all the CREOG educational requirements.  I also conduct case based learning sessions for the medical students throughout the year (2 hours per week).  I conduct journal club sessions with t
Alphabetical list of authors with Scholars@Duke profiles.
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