Associations between physical activity, sedentary behaviour and left ventricular structure and function from the Echocardiographic Study of Latinos (ECHO-SOL).
Abstract
The cross-sectional association between accelerometer-measured physical activity (PA),
sedentary behaviour (SB) and cardiac structure and function is less well described.
This study's primary aim was to compare echocardiographic measures of cardiac structure
and function with accelerometer measured PA and SB. Participants included 1206 self-identified
Hispanic/Latino men and women, age 45-74 years, from the Echocardiographic Study of
Latinos. Standard echocardiographic measures included M-mode, two-dimensional, spectral,
tissue Doppler and myocardial strain. Participants wore an Actical accelerometer at
the hip for 1 week. The mean±SE age for the cohort was 56±0.4 years, 57% were women.
Average moderate to vigorous PA (MVPA) was 21±1.1 min/day, light PA was 217±4.2 min/day
and SB was 737±8.1 min/day. Both higher levels of light PA and MVPA (min/day) were
associated with lower left ventricular (LV) mass index (LVMI)/end-diastolic volume
and a lower E/e' ratio. Higher levels of MVPA (min/day) were associated with better
right ventricular systolic function. Higher levels of SB were associated with increased
LVMI. In a multivariable linear regression model adjusted for demographics and cardiovascular
disease modifiable factors, every 10 additional min/day of light PA was associated
with a 0.03 mL/m2 increase in left atrial volume index (LAVI) (p<0.01) and a 0.004 cm
increase in tricuspid annular plane systolic excursion (p<0.01); every 10 additional
min/day of MVPA was associated with a 0.18 mL/m2 increase in LAVI (p<0.01) and a 0.24%
improvement in global circumferential strain (p<0.01). Our findings highlight the
potential positive association between the MVPA and light PA on cardiac structure
and function.
Type
Journal articleSubject
Heart VentriclesHumans
Cardiovascular Diseases
Echocardiography
Exercise
Population Surveillance
Morbidity
Follow-Up Studies
Prospective Studies
Cross-Sectional Studies
Adolescent
Adult
Aged
Middle Aged
United States
Female
Male
Young Adult
Accelerometry
Sedentary Behavior
Hispanic or Latino
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https://hdl.handle.net/10161/26048Published Version (Please cite this version)
10.1136/openhrt-2021-001647Publication Info
Berdy, Andrew E; Upadhya, Bharathi; Ponce, Sonia; Swett, Katrina; Stacey, Richard
B; Kaplan, Robert; ... Rodriguez, Carlos J (2021). Associations between physical activity, sedentary behaviour and left ventricular structure
and function from the Echocardiographic Study of Latinos (ECHO-SOL). Open heart, 8(2). pp. e001647. 10.1136/openhrt-2021-001647. Retrieved from https://hdl.handle.net/10161/26048.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
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Show full item recordScholars@Duke
Bharathi Upadhya
Associate Professor of Medicine

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