Now showing items 1-8 of 8

    • Common genetic variation and the control of HIV-1 in humans. 

      Antonarakis, SE; Beckmann, JS; Carrington, Mary; Castagna, A; Cirulli Rogers, Elizabeth T; Colombo, S; Cozzi-Lepri, A; ... (38 authors) (PLoS Genet, 2009-12)
      To extend the understanding of host genetic determinants of HIV-1 control, we performed a genome-wide association study in a cohort of 2,554 infected Caucasian subjects. The study was powered to detect common genetic variants ...
    • Comparative genomics reveals insights into avian genome evolution and adaptation 

      Alfaro-Núñez, A; Alström, P; An, N; Antunes, A; Bertelsen, MF; Borges, R; Braun, Edward L; ... (106 authors) (SCIENCE, 2014-12-12)
    • Comparative genomics reveals insights into avian genome evolution and adaptation. 

      Alfaro-Núñez, A; Alström, P; An, N; Antunes, A; Avian Genome Consortium; Bertelsen, MF; Borges, R; ... (106 authors) (Science, 2014-12-12)
      Birds are the most species-rich class of tetrapod vertebrates and have wide relevance across many research fields. We explored bird macroevolution using full genomes from 48 avian species representing all major extant clades. ...
    • Evolutionary genomics and adaptive evolution of the Hedgehog gene family (Shh, Ihh and Dhh) in vertebrates. 

      Antunes, A; Gilbert, M Thomas P; Jarvis, Erich David; Johnson, WE; O'Brien, Stephen J; Pereira, J; Vasconcelos, V; ... (8 authors) (PLoS One, 2014)
      The Hedgehog (Hh) gene family codes for a class of secreted proteins composed of two active domains that act as signalling molecules during embryo development, namely for the development of the nervous and skeletal systems ...
    • Gene loss, adaptive evolution and the co-evolution of plumage coloration genes with opsins in birds. 

      Antunes, A; Borges, R; Gilbert, M Thomas P; Jarvis, Erich David; Johnson, WE; Khan, I; O'Brien, Stephen J; ... (8 authors) (BMC Genomics, 2015-10-06)
      BACKGROUND: The wide range of complex photic systems observed in birds exemplifies one of their key evolutionary adaptions, a well-developed visual system. However, genomic approaches have yet to be used to disentangle the ...
    • Olfactory Receptor Subgenomes Linked with Broad Ecological Adaptations in Sauropsida. 

      Antunes, A; Gilbert, M Thomas P; Jarvis, Erich David; Johnson, WE; Khan, I; Li, C; Maldonado, E; ... (10 authors) (Mol Biol Evol, 2015-11)
      Olfactory receptors (ORs) govern a prime sensory function. Extant birds have distinct olfactory abilities, but the molecular mechanisms underlining diversification and specialization remain mostly unknown. We explored OR ...
    • The birds of Genome10K 

      Haussler, David; O'Brien, Stephen J; Ryder, Oliver A (GigaScience, 2014)
    • Whole-genome analyses resolve early branches in the tree of life of modern birds. 

      Aberer, AJ; Alfaro-Núñez, A; Alström, P; Bailey, T; Barker, FK; Bayzid, MS; Bertelsen, MF; ... (105 authors) (Science, 2014-12-12)
      To better determine the history of modern birds, we performed a genome-scale phylogenetic analysis of 48 species representing all orders of Neoaves using phylogenomic methods created to handle genome-scale data. We recovered ...