Browsing Duke Scholarly Works by Submit Date
Now showing items 1-20 of 13459
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Taxes and Subsidies and the Transition to Clean Cooking: A Review of Relevant Theoretical and Empirical Insights
(2022-11-22)United Nations Sustainable Development Goal 7.1 sets a target of ensuring universal access to affordable, reliable, and modern energy services by 2030. Unfortunately, many low- and middle-income countries (LMICs) are well ... -
State of the Coast: A Review of Coastal Management Policies for Six States
(2023-01-17)This analysis of coastal habitat policy in six US states—California, Florida, Massachusetts, North Carolina, Texas, and Washington—aims to identify promising policy approaches for improved protection and restoration of oyster ... -
Internally ratiometric fluorescent sensors for evaluation of intracellular GTP levels and distribution
(Nature Methods, 2017-10) -
Melanoma Suppressor Functions of the Carcinoma Oncogene FOXQ1
(Cell Reports, 2017-09) -
Inhibition of the aryl hydrocarbon receptor/polyamine biosynthesis axis suppresses multiple myeloma
(Journal of Clinical Investigation, 2018-09-10) -
The fatty acid elongase ELOVL6 regulates bortezomib resistance in multiple myeloma
(Blood Advances, 2021-04-13)<jats:title>Abstract</jats:title> <jats:p>Resistance to the proteasome inhibitor bortezomib (BTZ) represents a major obstacle in the treatment of multiple myeloma (MM). The contribution of lipid metabolism ... -
Regulation of local GTP availability controls RAC1 activity and cell invasion.
(Nature communications, 2021-10)Physiological changes in GTP levels in live cells have never been considered a regulatory step of RAC1 activation because intracellular GTP concentration (determined by chromatography or mass spectrometry) was shown to be ... -
Phosphorylation of guanosine monophosphate reductase triggers a GTP-dependent switch from pro- to anti-oncogenic function of EPHA4.
(Cell chemical biology, 2022-06)Signal transduction pathways post-translationally regulating nucleotide metabolism remain largely unknown. Guanosine monophosphate reductase (GMPR) is a nucleotide metabolism enzyme that decreases GTP pools by converting ... -
Compartmentalization and regulation of GTP in control of cellular phenotypes.
(Trends in molecular medicine, 2022-09)Genetic or pharmacological inhibition of enzymes involved in GTP biosynthesis has substantial biological effects, underlining the need to better understand the function of GTP levels in regulation of cellular processes and ... -
Beyond “See Figure 1”: A Heuristic for Writing About Figures and Tables
(Journal of College Science Teaching, 2023-02-01)Visual elements such as graphs, tables, and diagrams are essential components of scientific writing. Although scientific writing textbooks and guides often contain information on how to design such visuals, little has been ... -
Ganbare! Workshops on Dying
(LITERARY JOURNALISM STUDIES, 2022) -
Concordance Between Genomic Alterations Detected by Tumor and Germline Sequencing: Results from a Tertiary Care Academic Center Molecular Tumor Board.
(The oncologist, 2023-01)<h4>Objective</h4>The majority of tumor sequencing currently performed on cancer patients does not include a matched normal control, and in cases where germline testing is performed, it is usually run independently of tumor ... -
Stabilized HIV-1 envelope immunization induces neutralizing antibodies to the CD4bs and protects macaques against mucosal infection.
(Science translational medicine, 2022-09)A successful HIV-1 vaccine will require induction of a polyclonal neutralizing antibody (nAb) response, yet vaccine-mediated induction of such a response in primates remains a challenge. We found that a stabilized HIV-1 ... -
A Preliminary Psychometric Analysis of the Difficulties with Emotion Regulation Scale (DERS) Among Autistic Adolescents and Adults: Factor Structure, Reliability, and Validity.
(Journal of autism and developmental disorders, 2022-03)Emotion dysregulation is common among autistic people, yet few measures have received psychometric evaluation in this population. We examined the factor structure, reliability, and validity of a commonly-used measure of ... -
Females have Lower Knee Strength and Vertical Ground Reaction Forces During Landing than Males Following Anterior Cruciate Ligament Reconstruction at the Time of Return to Sport.
(International journal of sports physical therapy, 2022-01)<h4>Purpose</h4>There is a high rate of second anterior cruciate ligament (ACL) injury (ipsilateral graft or contralateral ACL) upon return-to-sport (RTS) following ACL reconstruction (ACLR). While a significant amount of ... -
Isometric Knee Strength is Greater in Individuals Who Score Higher on Psychological Readiness to Return to Sport After Primary Anterior Cruciate Ligament Reconstruction.
(International journal of sports physical therapy, 2022-01)<h4>Background</h4>Anterior cruciate ligament (ACL) injury is extremely common among athletes. Rate of second ACL injury due to surgical graft rupture or contralateral limb ACL injury is approximately 15-32%. Psychological ... -
Correction to: The Society for Implementation Research Collaboration Instrument Review Project: a methodology to promote rigorous evaluation.
(Implementation science : IS, 2020-01)Following publication of the original article [1] the authors reported an important acknowledgement was mistakenly omitted from the 'Acknowledgements' section. The full acknowledgement is included in this Correction article. -
Tryptophan Metabolism and Neurodegeneration: Longitudinal Associations of Kynurenine Pathway Metabolites with Cognitive Performance and Plasma Alzheimer's Disease and Related Dementias Biomarkers in the Duke Physical Performance Across the LifeSpan Study.
(Journal of Alzheimer's disease : JAD, 2022-12)<h4>Background</h4>The kynurenine pathway (KP) comprises a family of tryptophan-derived metabolites that some studies have reported are associated with poorer cognitive performance and an increased risk of Alzheimer's disease ... -
Type-2 diabetes, pancreatic amylin and neuronal metabolic remodeling in Alzheimer's Disease.
(Mol Nutr Food Res, 2023-01-28)Type-2 diabetes raises the risk for Alzheimer's disease (AD)-type dementia and the conversion from mild cognitive impairment to dementia, yet mechanisms connecting type-2 diabetes to AD remain largely unknown. Amylin, a ...
