Now showing items 1-5 of 5

    • Design, recruitment, logistics, and data management of the GEHA (Genetics of Healthy Ageing) project. 

      Balard, F; Beekman, M; Bezrukov, V; Blanche, H; Bolund, L; Broczek, K; Carru, C; ... (59 authors) (Exp Gerontol, 2011-11)
      In 2004, the integrated European project GEHA (Genetics of Healthy Ageing) was initiated with the aim of identifying genes involved in healthy ageing and longevity. The first step in the project was the recruitment of more ...
    • Ecological restoration of rich fens in Europe and North America: from trial and error to an evidence-based approach. 

      Acreman, MC; Evans, MG; Grootjans, AP; Kooijman, AM; Lamers, LPM; Richardson, Curtis J; Rochefort, L; ... (11 authors) (Biol Rev Camb Philos Soc, 2015-02)
      Fens represent a large array of ecosystem services, including the highest biodiversity found among wetlands, hydrological services, water purification and carbon sequestration. Land-use change and drainage has severely damaged ...
    • Focal therapy in prostate cancer-report from a consensus panel. 

      Ahmed, H; Barentsz, J; Brausi, M; de la Rosette, J; de Reijke, T; Emberton, M; Frauscher, F; ... (22 authors) (J Endourol, 2010-05)
      PURPOSE: To establish a consensus in relation to case selection, conduct of therapy, and outcomes that are associated with focal therapy for men with localized prostate cancer. MATERIAL AND METHODS: Urologic surgeons, radiation ...
    • Genome-wide linkage analysis for human longevity: Genetics of Healthy Aging Study. 

      Ayers, KL; Beekman, M; Bezrukov, V; Blanché, H; Christensen, Kaare; Christiansen, L; Cordell, HJ; ... (41 authors) (Aging Cell, 2013-04)
      Clear evidence exists for heritability of human longevity, and much interest is focused on identifying genes associated with longer lives. To identify such longevity alleles, we performed the largest genome-wide linkage ...
    • The quantity and quality of worldwide new drug introductions, 1982-2003. 

      Grabowski, Henry G; Wang, YR (Health Aff (Millwood), 2006-03)
      We examined trends in the introduction of new chemical entities (NCEs) worldwide from 1982 through 2003. Although annual introductions of NCEs decreased over time, introductions of high-quality NCEs (that is, global and ...