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Toward development of a comprehensive external quality assurance program for polyfunctional intracellular cytokine staining assays.
(J Immunol Methods, 2014-07)
The External Quality Assurance Program Oversight Laboratory (EQAPOL) Flow Cytometry
Program assesses the proficiency of NIH/NIAID/DAIDS-supported and potentially other
interested research laboratories in performing Intracellular ...
Association of Common Genetic Polymorphisms with Melanoma Patient IL-12p40 Blood Levels, Risk, and Outcomes
(JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2015-09)
Diet-induced obesity differentially regulates behavioral, biomechanical, and molecular risk factors for osteoarthritis in mice.
(Arthritis Res Ther, 2010)
INTRODUCTION: Obesity is a major risk factor for the development of osteoarthritis
in both weight-bearing and nonweight-bearing joints. The mechanisms by which obesity
influences the structural or symptomatic features of ...
Hypertension and obesity as cardiovascular risk factors among HIV seropositive patients in Western Kenya.
(PLoS One, 2011)
BACKGROUND: There is increased risk of cardiovascular disease among HIV seropositive
individuals. The prevalence of HIV is highest in sub-Saharan Africa; however, HIV-related
cardiovascular risk research is largely derived ...
Development of a contemporary globally diverse HIV viral panel by the EQAPOL program
(Journal of Immunological Methods, 2014-01-01)
The significant diversity among HIV-1 variants poses serious challenges for vaccine
development and for developing sensitive assays for screening, surveillance, diagnosis,
and clinical management. Recognizing a need to develop ...
A pilot randomized controlled trial with paroxetine for subthreshold PTSD in Operation Enduring Freedom/Operation Iraqi Freedom era veterans.
(Psychiatry Res, 2013-04-30)
Subthreshold posttraumatic stress disorder (PTSD) is associated with increased risk
for suicidality, depression, and functional impairment. We thus conducted a small
(N=12) pilot randomized controlled trial (RCT) with paroxetine ...
Effects of chronic mild traumatic brain injury on white matter integrity in iraq and afghanistan war veterans
(Human Brain Mapping, 2013-11-01)
Mild traumatic brain injury (TBI) is a common source of morbidity from the wars in
Iraq and Afghanistan. With no overt lesions on structural MRI, diagnosis of chronic
mild TBI in military veterans relies on obtaining an ...
Multifactorial determinants of the neurocognitive effects of electroconvulsive therapy.
(J ECT, 2014-06)
For many patients with neuropsychiatric illnesses, standard psychiatric treatments
with mono or combination pharmacotherapy, psychotherapy, and transcranial magnetic
stimulation are ineffective. For these patients ...
Leukopak PBMC sample processing for preparing quality control material to support proficiency testing programs
(Journal of Immunological Methods, 2014-01-01)
External proficiency testing programs designed to evaluate the performance of end-point
laboratories involved in vaccine and therapeutic clinical trials form an important
part of clinical trial quality assurance. Good clinical ...
Pathogenesis of growth failure and partial reversal with gene therapy in murine and canine Glycogen Storage Disease type Ia.
(Mol Genet Metab, 2013-06)
Glycogen Storage Disease type Ia (GSD-Ia) in humans frequently causes delayed bone
maturation, decrease in final adult height, and decreased growth velocity. This study
evaluates the pathogenesis of growth failure and the ...