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Toward development of a comprehensive external quality assurance program for polyfunctional intracellular cytokine staining assays. 

Chan, C; Chan, RC-F; Denny, Thomas Norton; Enzor, Jennifer; Gaur, A; Jaimes, M; Rountree, Wes; ... (10 authors) (J Immunol Methods, 2014-07)
The External Quality Assurance Program Oversight Laboratory (EQAPOL) Flow Cytometry Program assesses the proficiency of NIH/NIAID/DAIDS-supported and potentially other interested research laboratories in performing Intracellular ...
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Association of Common Genetic Polymorphisms with Melanoma Patient IL-12p40 Blood Levels, Risk, and Outcomes 

Fang, S; Wang, Y; Chun, YS; Liu, H; Ross, MI; Gershenwald, JE; Cormier, JN; ... (18 authors) (JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2015-09)
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Diet-induced obesity differentially regulates behavioral, biomechanical, and molecular risk factors for osteoarthritis in mice. 

Cao, L; Fermor, B; Griffin, TM; Guilak, Farshid; Huebner, JL; Kraus, Virginia Byers; Rodriguiz, Ramona M; ... (9 authors) (Arthritis Res Ther, 2010)
INTRODUCTION: Obesity is a major risk factor for the development of osteoarthritis in both weight-bearing and nonweight-bearing joints. The mechanisms by which obesity influences the structural or symptomatic features of ...
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Hypertension and obesity as cardiovascular risk factors among HIV seropositive patients in Western Kenya. 

Bloomfield, Gerald; Carter, EJ; Hogan, JW; Keter, A; Kimaiyo, S; Sang, E; Velazquez, Eric J (PLoS One, 2011)
BACKGROUND: There is increased risk of cardiovascular disease among HIV seropositive individuals. The prevalence of HIV is highest in sub-Saharan Africa; however, HIV-related cardiovascular risk research is largely derived ...
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Development of a contemporary globally diverse HIV viral panel by the EQAPOL program 

Brinkley, Christie; Busch, Michael P; Chen, Y; Demarco, C Todd; Denny, Thomas Norton; Gao, Feng; Hora, Bhavna; ... (13 authors) (Journal of Immunological Methods, 2014-01-01)
The significant diversity among HIV-1 variants poses serious challenges for vaccine development and for developing sensitive assays for screening, surveillance, diagnosis, and clinical management. Recognizing a need to develop ...
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Leukopak PBMC sample processing for preparing quality control material to support proficiency testing programs 

Denny, Thomas Norton; Ferrari, Guido; Garcia, Ambrosia; Keinonen, Sarah; Moody, M Anthony; Sanchez, Ana M (Journal of Immunological Methods, 2014-01-01)
External proficiency testing programs designed to evaluate the performance of end-point laboratories involved in vaccine and therapeutic clinical trials form an important part of clinical trial quality assurance. Good clinical ...
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A prospective comparison of a noninvasive cardiac output monitor versus esophageal doppler monitor for goal-directed fluid therapy in colorectal surgery patients 

Elgasim, Magdi; Gan, Tong Joo; Manchester, Amy Kantipong; Miller, Timothy Ellis; Moon, Richard Edward; Nardiello, John; Thacker, Julie K Marosky; ... (9 authors) (Anesthesia and Analgesia, 2014-01-01)
Copyright © 2014 International Anesthesia Research Society.BACKGROUND: Goal-directed fluid therapy (GDFT) is associated with improved outcomes after surgery. The esophageal Doppler monitor (EDM) is widely used, but has several ...
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Statistical methods for the assessment of EQAPOL proficiency testing: ELISpot, Luminex, and Flow Cytometry 

Bain, James R; Denny, Thomas Norton; Rountree, Wes; Sanchez, Ana M; Vandergrift, Nathan A (Journal of Immunological Methods, 2014-01-01)
In September 2011 Duke University was awarded a contract to develop the National Institutes of Health/National Institute of Allergy and Infectious Diseases (NIH/NIAID) External Quality Assurance Program Oversight Laboratory ...
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Establishment and maintenance of a PBMC repository for functional cellular studies in support of clinical vaccine trials. 

Berrong, Mark; Brown, S; Cox, J; D'Souza, M Patricia; Denny, Thomas Norton; Ferrari, Guido; Frahm, N; ... (19 authors) (J Immunol Methods, 2014-07)
A large repository of cryopreserved peripheral blood mononuclear cells (PBMCs) samples was created to provide laboratories testing the specimens from human immunodeficiency virus-1 (HIV-1) vaccine clinical trials the material ...
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Introduction to a Special Issue of the Journal of Immunological Methods: Building Global Resource Programs to Support HIV/AIDS Clinical Trial Studies 

Denny, Thomas Norton; O'Gorman, Maurice; Sanchez, Ana M (Journal of Immunological Methods, 2014)
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