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Continuous intravenous cimetidine decreases stress-related upper gastrointestinal hemorrhage without promoting pneumonia.

Martin, LF; Booth, FV; Karlstadt, RG; Silverstein, JH; Jacobs, DM; Hampsey, J; Bowman, SC; ... (9 authors) (Crit Care Med, 1993-01)

OBJECTIVES: To determine whether a continuous i.v. infusion of cimetidine, a histamine-2 (H2) receptor antagonist, is needed to prevent upper gastrointestinal (GI) hemorrhage when compared with placebo and if that usage ...