Now showing items 1-10 of 192
Emergency department point-of-care ultrasound in out-of-hospital and in-ED cardiac arrest.
Point-of-care ultrasound has been suggested to improve outcomes from advanced cardiac life support (ACLS), but no large studies have explored how it should be incorporated into ACLS. Our aim was to determine whether cardiac ...
Molecular genetic testing and the future of clinical genomics.
(Nature reviews. Genetics, 2013-06)
Genomic technologies are reaching the point of being able to detect genetic variation in patients at high accuracy and reduced cost, offering the promise of fundamentally altering medicine. Still, although scientists and ...
A putatively functional polymorphism in the HTR2C gene is associated with depressive symptoms in white females reporting significant life stress.
(PloS one, 2014-01)
Psychosocial stress is well known to be positively associated with subsequent depressive symptoms. Cortisol response to stress may be one of a number of biological mechanisms that links psychological stress to depressive ...
Providing successful faculty development to graduate medical education program directors.
(International journal of medical education, 2017-09-11)
The Emergency Department as an Opportunity for Naloxone Distribution.
(The western journal of emergency medicine, 2018-11)
Introduction:Substance use disorders, including opioid use disorders, are a major public health concern in the United States. Between 2005 and 2014, the rate of opioid-related emergency department (ED) visits nearly doubled, ...
Exposure to opposing views on social media can increase political polarization.
(Proceedings of the National Academy of Sciences of the United States of America, 2018-09)
There is mounting concern that social media sites contribute to political polarization by creating "echo chambers" that insulate people from opposing views about current events. We surveyed a large sample of Democrats and ...
Association between novel PLCE1 variants identified in published esophageal cancer genome-wide association studies and risk of squamous cell carcinoma of the head and neck.
(BMC cancer, 2011-06-20)
Phospholipase C epsilon 1 (PLCE1) (an effector of Ras) belonging to the phospholipase family plays crucial roles in carcinogenesis and progression of several cancers, including squamous cell carcinoma of the head and neck ...
Sinus Node Dysfunction Is Associated With Higher Symptom Burden and Increased Comorbid Illness: Results From the ORBIT-AF Registry.
(Clin Cardiol, 2016-02)
BACKGROUND: Patients with sinus node dysfunction (SND) have increased risk of atrial tachyarrhythmias, including atrial fibrillation (AF). To date, treatment patterns and outcomes of patients with SND and AF have not been ...
PhenX RISING: real world implementation and sharing of PhenX measures.
(BMC Med Genomics, 2014-03-20)
BACKGROUND: The purpose of this manuscript is to describe the PhenX RISING network and the site experiences in the implementation of PhenX measures into ongoing population-based genomic studies. METHODS: Eighty PhenX measures ...
Recovery and survival from aging-associated diseases.
(Exp Gerontol, 2013-08)
OBJECTIVES: Considering disease incidence to be a main contributor to healthy lifespan of the US elderly population may lead to erroneous conclusions when recovery/long-term remission factors are underestimated. Using two ...