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Now showing items 1-10 of 13
The ORBIT bleeding score: a simple bedside score to assess bleeding risk in atrial fibrillation.
(Eur Heart J, 2015-12-07)
BACKGROUND: Therapeutic decisions in atrial fibrillation (AF) are often influenced
by assessment of bleeding risk. However, existing bleeding risk scores have limitations.
OBJECTIVES: We sought to develop and validate a ...
Plasma antibodies against heat shock protein 70 correlate with the incidence and severity of asthma in a Chinese population.
(Respiratory research, 2005-01)
BACKGROUND: The heat shock proteins (Hsps) are induced by stresses such as allergic
factors and inflammatory responses in bronchi epithelial cells and therefore may be
detectable in patients with asthma. However, the etiologic ...
Risk Factors for Heart Failure in Patients With Chronic Kidney Disease: The CRIC (Chronic Renal Insufficiency Cohort) Study.
(Journal of the American Heart Association, 2017-05-17)
BACKGROUND:Heart failure is common in patients with chronic kidney disease. We studied
risk factors for incident heart failure among 3557 participants in the CRIC (Chronic
Renal Insufficiency Cohort) Study. METHODS ...
Genome-wide association study of acute kidney injury after coronary bypass graft surgery identifies susceptibility loci.
(Kidney Int, 2015-10)
Acute kidney injury (AKI) is a common, serious complication of cardiac surgery. Since
prior studies have supported a genetic basis for postoperative AKI, we conducted a
genome-wide association study (GWAS) for AKI following ...
Pulmonary hypertension and elevated transpulmonary gradient in patients with mitral stenosis.
(J Heart Valve Dis, 2010-11)
BACKGROUND AND AIM OF THE STUDY: Pulmonary hypertension frequently complicates mitral
stenosis, with a subset of these patients exhibiting pressures well in excess of their
mitral valve hemodynamics. The prevalence of this ...
A risk score for in-hospital death in patients admitted with ischemic or hemorrhagic stroke.
(J Am Heart Assoc, 2013-01-28)
BACKGROUND: We aimed to derive and validate a single risk score for predicting death
from ischemic stroke (IS), intracerebral hemorrhage (ICH), and subarachnoid hemorrhage
(SAH). METHODS AND RESULTS: Data from 333 865 stroke ...
Long-term dynamics of death rates of emphysema, asthma, and pneumonia and improving air quality.
(Int J Chron Obstruct Pulmon Dis, 2014)
BACKGROUND: The respiratory tract is a major target of exposure to air pollutants,
and respiratory diseases are associated with both short- and long-term exposures.
We hypothesized that improved air quality in North Carolina ...
Relationship Between Cancer and Cardiovascular Outcomes Following Percutaneous Coronary Intervention.
(J Am Heart Assoc, 2015-07-06)
BACKGROUND: Cardiovascular disease and cancer increasingly coexist, yet relationships
between cancer and long-term cardiovascular outcomes post-percutaneous coronary intervention
(PCI) are not well studied. METHODS AND RESULTS: ...
Associations between expression levels of nucleotide excision repair proteins in lymphoblastoid cells and risk of squamous cell carcinoma of the head and neck.
(Molecular carcinogenesis, 2018-06)
Squamous cell carcinoma of head and neck (SCCHN) is one of the most common malignancies
worldwide, and nucleotide excision repair (NER) is involved in SCCHN susceptibility.
In this analysis of 349 newly diagnosed SCCHN patients ...
Effect of genetic testing for risk of type 2 diabetes mellitus on health behaviors and outcomes: study rationale, development and design.
(BMC Health Serv Res, 2012-01-18)
BACKGROUND: Type 2 diabetes is a prevalent chronic condition globally that results
in extensive morbidity, decreased quality of life, and increased health services utilization.
Lifestyle changes can prevent the development ...