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Hypertension and obesity as cardiovascular risk factors among HIV seropositive patients in Western Kenya.
(PLoS One, 2011)
BACKGROUND: There is increased risk of cardiovascular disease among HIV seropositive
individuals. The prevalence of HIV is highest in sub-Saharan Africa; however, HIV-related
cardiovascular risk research is largely derived ...
Clinical characteristics and 12-month outcomes of patients with valvular and non-valvular atrial fibrillation in Kenya.
(PLoS One, 2017)
BACKGROUND: Atrial fibrillation (AF) is a major contributor to the global cardiovascular
disease burden. The clinical profile and outcomes of AF patients with valvular heart
diseases in sub-Saharan Africa (SSA) have not ...
Comparative effectiveness studies to improve clinical outcomes in end stage renal disease: the DEcIDE patient outcomes in end stage renal disease study.
(BMC Nephrol, 2012-12-06)
BACKGROUND: Evidence is lacking to inform providers' and patients' decisions about
many common treatment strategies for patients with end stage renal disease (ESRD).
METHODS/DESIGN: The DEcIDE Patient Outcomes in ESRD Study ...
Impact of increases in high-density lipoprotein cholesterol on cardiovascular outcomes during the armed forces regression study.
(J Cardiovasc Pharmacol Ther, 2010-12)
INTRODUCTION: high-density lipoprotein (HDL) cholesterol is a well-established inverse
risk factor for cardiovascular disease. The extent to which cardiovascular risk can
be modified through changes in HDL, however, is less ...
Traditional medicine practices among community members with chronic kidney disease in northern Tanzania: an ethnomedical survey.
(BMC Nephrol, 2015-10-23)
BACKGROUND: In sub-Saharan Africa, chronic kidney disease (CKD) is being recognized
as a non-communicable disease (NCD) with high morbidity and mortality. In countries
like Tanzania, people access many sources, including ...
A genetic variant in the APE1/Ref-1 gene promoter -141T/G may modulate risk of glioblastoma in a Chinese Han population.
(BMC cancer, 2011-01)
BACKGROUND: The human apurinic/apyrimidinic endonuclease 1/Redox effector factor-1
(APE1/Ref-1) is implicated in tumor development and progression. Recently, the APE1/Ref-1
promoter -141T/G variant (rs1760944) has been reported ...
On the interplay of telomeres, nevi and the risk of melanoma.
(PloS one, 2012-01)
The relationship between telomeres, nevi and melanoma is complex. Shorter telomeres
have been found to be associated with many cancers and with number of nevi, a known
risk factor for melanoma. However, shorter telomeres ...
Associations of potentially functional variants in IL-6, JAKs and STAT3 with gastric cancer risk in an eastern Chinese population.
(Oncotarget, 2016-05)
The interleukin-6 (IL-6)/JAK/STAT3 signaling pathway plays a central role in inflammation-mediated
cancers, including gastric cancer (GCa). We evaluated associations between 10 potentially
functional single nucleotide ...
Risk Factors for Heart Failure in Patients With Chronic Kidney Disease: The CRIC (Chronic Renal Insufficiency Cohort) Study.
(Journal of the American Heart Association, 2017-05-17)
BACKGROUND:Heart failure is common in patients with chronic kidney disease. We studied
risk factors for incident heart failure among 3557 participants in the CRIC (Chronic
Renal Insufficiency Cohort) Study. METHODS ...
National trends and characteristics of inpatient detoxification for drug use disorders in the United States.
(BMC public health, 2018-08-29)
BACKGROUND:Prior studies indicate that the opportunity from detoxification to engage
in subsequent drug use disorder (DUD) treatment may be missed. This study examined
national trends and characteristics of inpatient ...