Now showing items 1-10 of 2917
How Oncology Fellows Discuss Transitions in Goals of Care: A Snapshot of Approaches Used Prior to Training
(Journal of Palliative Medicine, 2010-04)
Communication practices in physician decision-making for an unstable critically ill patient with end-stage cancer.
(J Palliat Med, 2010-08)
BACKGROUND: Shared decision-making has become the standard of care for most medical treatments. However, little is known about physician communication practices in the decision making for unstable critically ill patients ...
Auriculotherapy for pain management: a systematic review and meta-analysis of randomized controlled trials.
(J Altern Complement Med, 2010-10)
OBJECTIVES: Side-effects of standard pain medications can limit their use. Therefore, nonpharmacologic pain relief techniques such as auriculotherapy may play an important role in pain management. Our aim was to conduct ...
Dual-energy computed tomography with advanced postimage acquisition data processing: improved determination of urinary stone composition.
(J Endourol, 2010-03)
INTRODUCTION: The characterization of urinary calculi using noninvasive methods has the potential to affect clinical management. CT remains the gold standard for diagnosis of urinary calculi, but has not reliably differentiated ...
Daily intake of antioxidants in relation to survival among adult patients diagnosed with malignant glioma.
(BMC Cancer, 2010-05-19)
BACKGROUND: Malignant glioma is a rare cancer with poor survival. The influence of diet and antioxidant intake on glioma survival is not well understood. The current study examines the association between antioxidant intake ...
Ligation of cell surface GRP78 with antibody directed against the COOH-terminal domain of GRP78 suppresses Ras/MAPK and PI 3-kinase/AKT signaling while promoting caspase activation in human prostate cancer cells.
(Cancer Biol Ther, 2010-01)
We have previously shown that treatment of prostate cancer and melanoma cells expressing GRP78 on their cell surface with antibody directed against the COOH-terminal domain of GRP78 upregulates and activates p53 causing ...
Quality control autophagy: a joint effort of ubiquitin, protein deacetylase and actin cytoskeleton.
Autophagy has been predominantly studied as a nonselective self-digestion process that recycles macromolecules and produces energy in response to starvation. However, autophagy independent of nutrient status has long been ...
VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD.
VCP (VCP/p97) is a ubiquitously expressed member of the AAA(+)-ATPase family of chaperone-like proteins that regulates numerous cellular processes including chromatin decondensation, homotypic membrane fusion and ...
How anthropological theory and methods can advance global mental health.
(Lancet Psychiatry, 2016-05)
Detection of depression in low resource settings: validation of the Patient Health Questionnaire (PHQ-9) and cultural concepts of distress in Nepal.
(BMC Psychiatry, 2016-03-08)
BACKGROUND: Despite recognition of the burden of disease due to mood disorders in low- and middle-income countries, there is a lack of consensus on best practices for detecting depression. Self-report screening tools, such ...