Now showing items 1-10 of 976
Cooperativity between the phosphorylation of Thr95 and Ser77 of NHERF-1 in the hormonal regulation of renal phosphate transport.
(The Journal of biological chemistry, 2010-08)
The phosphorylation of the sodium-hydrogen exchanger regulatory factor-1 (NHERF-1) plays a key role in the regulation of renal phosphate transport by parathyroid hormone (PTH) and dopamine. Ser(77) in the first PDZ domain ...
Diet-induced obesity differentially regulates behavioral, biomechanical, and molecular risk factors for osteoarthritis in mice.
(Arthritis Res Ther, 2010)
INTRODUCTION: Obesity is a major risk factor for the development of osteoarthritis in both weight-bearing and nonweight-bearing joints. The mechanisms by which obesity influences the structural or symptomatic features of ...
Biogeography in deep time - What do phylogenetics, geology, and paleoclimate tell us about early platyrrhine evolution?
(Mol Phylogenet Evol, 2015-01)
Molecular data have converged on a consensus about the genus-level phylogeny of extant platyrrhine monkeys, but for most extinct taxa and certainly for those older than the Pleistocene we must rely upon morphological evidence ...
Pathogenesis of growth failure and partial reversal with gene therapy in murine and canine Glycogen Storage Disease type Ia.
(Mol Genet Metab, 2013-06)
Glycogen Storage Disease type Ia (GSD-Ia) in humans frequently causes delayed bone maturation, decrease in final adult height, and decreased growth velocity. This study evaluates the pathogenesis of growth failure and the ...
Evidence-ranked motif identification.
(Genome Biol, 2010)
cERMIT is a computationally efficient motif discovery tool based on analyzing genome-wide quantitative regulatory evidence. Instead of pre-selecting promising candidate sequences, it utilizes information across all sequence ...
Oldest known cranium of a juvenile New World monkey (Early Miocene, Patagonia, Argentina): implications for the taxonomy and the molar eruption pattern of early platyrrhines.
(J Hum Evol, 2014-09)
A juvenile cranium of Homunculus patagonicus Ameghino, 1891a from the late Early Miocene of Santa Cruz Province (Argentina) provides the first evidence of developing cranial anatomy for any fossil platyrrhine. The specimen ...
Body temperature and thermal environment in a generalized arboreal anthropoid, wild mantled howling monkeys (Alouatta palliata).
(Am J Phys Anthropol, 2014-05)
Free-ranging primates are confronted with the challenge of maintaining an optimal range of body temperatures within a thermally dynamic environment that changes daily, seasonally, and annually. While many laboratory studies ...
Anthropology. New World monkey origins.
Rapid, accurate time estimation in zebrafish (Danio rerio).
(Behav Processes, 2013-10)
Zebrafish were tested in an appetitive Pavlovian delayed conditioning task. After an intertrial interval of k*T s (k=11.25; T=8, 16 or 32 s), a small, translucent vertical pole was illuminated (CS) for T s. Food was presented ...
The pallial basal ganglia pathway modulates the behaviorally driven gene expression of the motor pathway.
(Eur J Neurosci, 2007-04)
The discrete neural network for songbird vocal communication provides an effective system to study neural mechanisms of learned motor behaviors in vertebrates. This system consists of two pathways--a vocal motor pathway ...