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Now showing items 1-10 of 12

A randomized controlled trial of standard versus intensified tuberculosis diagnostics on treatment decisions by physicians in Northern Tanzania.

Bartlett, John A; Chow, S-C; Crump, John Andrew; Cunningham, Coleen; Hamilton, Carol; Kibiki, Gibson S; Lancaster, KE; ... (18 authors) (BMC Infect Dis, 2014-02-20)

BACKGROUND: Routine tuberculosis culture remains unavailable in many high-burden areas, including Tanzania. This study sought to determine the impact of providing mycobacterial culture results over standard of care ...

Initiation of antiretroviral therapy in HIV-infected adults with skin complaints in northern Tanzania.

Bartlett, John A; Crump, John Andrew; Grossmann, H; Masenga, EJ; Mavura, DR; Minja, E (Int J Dermatol, 2015-01)

Abnormal skin findings are identified in over 90% of human immunodeficiency virus (HIV)-infected persons globally. A prospective cohort study of HIV-infected patients with skin complaints commencing antiretroviral therapy ...

Lopinavir/Ritonavir Monotherapy as Second-line Antiretroviral Treatment in Resource-Limited Settings: Week 104 Analysis of AIDS Clinical Trials Group (ACTG) A5230.

Aga, E; Badal-Faesen, S; Bartlett, John A; Crump, John Andrew; Hosseinipour, MC; Katzenstein, DA; Klingman, KL; ... (13 authors) (Clin Infect Dis, 2015-05-15)

BACKGROUND: The AIDS Clinical Trials Group (ACTG) A5230 study evaluated lopinavir/ritonavir (LPV/r) monotherapy following virologic failure (VF) on first-line human immunodeficiency virus (HIV) regimens in Africa and Asia. ...

Bacteremic disseminated tuberculosis in sub-saharan Africa: a prospective cohort study.

Bartlett, John A; Chow, S-C; Crump, John Andrew; Maro, Venance P; Morrissey, AB; Mushi, GS; Mwako, MS; ... (12 authors) (Clin Infect Dis, 2012-07)

BACKGROUND: Disseminated tuberculosis is a major health problem in countries where generalized human immunodeficiency virus (HIV) infection epidemics coincide with high tuberculosis incidence rates; data are limited on patient ...

Changes in HIV risk behavior and seroincidence among clients presenting for repeat HIV counseling and testing in Moshi, Tanzania.

Crump, John Andrew; Fiorillo, SP; Itemba, DK; Landman, KZ; Mtalo, A; Ostermann, Jan; Thielman, Nathan Maclyn; ... (8 authors) (AIDS Care, 2012)

While HIV counseling and testing (HCT) has been considered an HIV preventive measure in Africa, data are limited describing behavior changes following HCT. This study evaluated behavior changes and estimated HIV seroincidence ...

Brucellosis among hospitalized febrile patients in northern Tanzania.

Afwamba, IA; Bartlett, John A; Biggs, HM; Bouley, AJ; Cleaveland, S; Crump, John Andrew; Kinabo, GD; ... (11 authors) (Am J Trop Med Hyg, 2012-12)

Acute and convalescent serum samples were collected from febrile inpatients identified at two hospitals in Moshi, Tanzania. Confirmed brucellosis was defined as a positive blood culture or a ≥ 4-fold increase in ...

Lopinavir/ritonavir monotherapy after virologic failure of first-line antiretroviral therapy in resource-limited settings.

Aga, E; Badal-Faesen, S; Bartlett, John A; Crump, John Andrew; Hosseinipour, MC; Kallungal, BA; Katzenstein, DA; ... (14 authors) (AIDS, 2012-07-17)

OBJECTIVE: To evaluate virologic response rates of lopinavir/ritonavir (LPV/r) monotherapy as second-line antiretroviral treatment (ART) among adults in resource-limited settings (RLSs). DESIGN: An open-label pilot study ...

Leptospirosis among hospitalized febrile patients in northern Tanzania.

Bartlett, John A; Biggs, HM; Bui, DM; Crump, John Andrew; Galloway, RL; Kinabo, GD; Maro, Venance P; ... (12 authors) (Am J Trop Med Hyg, 2011-08)

We enrolled consecutive febrile admissions to two hospitals in Moshi, Tanzania. Confirmed leptospirosis was defined as a ≥ 4-fold increase in microscopic agglutination test (MAT) titer; probable leptospirosis as reciprocal ...

Initial HIV-1 antigen-specific CD8+ T cells in acute HIV-1 infection inhibit transmitted/founder virus replication.

Cohen, MS; Crump, John Andrew; Cunningham, Coleen; Denny, Thomas Norton; Ding, Haitao; Ferrari, Guido; Freel, SA; ... (16 authors) (J Virol, 2012-06)

CD8-mediated virus inhibition can be detected in HIV-1-positive subjects who naturally control virus replication. Characterizing the inhibitory function of CD8(+) T cells during acute HIV-1 infection (AHI) can elucidate ...

Etiologies of illness among patients meeting integrated management of adolescent and adult illness district clinician manual criteria for severe infections in northern Tanzania: implications for empiric antimicrobial therapy.

Bartlett, John A; Crump, John Andrew; Maro, Venance P; Rubach, MP (Am J Trop Med Hyg, 2015-02)

We describe the laboratory-confirmed etiologies of illness among participants in a hospital-based febrile illness cohort study in northern Tanzania who retrospectively met Integrated Management of Adolescent and Adult Illness ...