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Hypertension and obesity as cardiovascular risk factors among HIV seropositive patients in Western Kenya.
(PLoS One, 2011)
BACKGROUND: There is increased risk of cardiovascular disease among HIV seropositive
individuals. The prevalence of HIV is highest in sub-Saharan Africa; however, HIV-related
cardiovascular risk research is largely derived ...
Association between novel PLCE1 variants identified in published esophageal cancer genome-wide association studies and risk of squamous cell carcinoma of the head and neck.
(BMC cancer, 2011-06-20)
Phospholipase C epsilon 1 (PLCE1) (an effector of Ras) belonging to the phospholipase
family plays crucial roles in carcinogenesis and progression of several cancers, including
squamous cell carcinoma of the head and neck ...
A genetic variant in the APE1/Ref-1 gene promoter -141T/G may modulate risk of glioblastoma in a Chinese Han population.
(BMC cancer, 2011-01)
BACKGROUND: The human apurinic/apyrimidinic endonuclease 1/Redox effector factor-1
(APE1/Ref-1) is implicated in tumor development and progression. Recently, the APE1/Ref-1
promoter -141T/G variant (rs1760944) has been reported ...
A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium.
(PLoS genetics, 2011-03-17)
Genome-wide association studies (GWAS) have been successful in identifying common
genetic variation involved in susceptibility to etiologically complex disease. We
conducted a GWAS to identify common genetic variation involved ...
Illicit and nonmedical drug use among older adults: a review.
(Journal of aging and health, 2011-04)
Substance abuse among older adults is a looming public health concern. The number
of Americans aged 50+ years with a substance use disorder is projected to double from
2.8 million in 2002-2006 to 5.7 million in 2020. The ...
Depressive symptoms, substance use, and HIV-related high-risk behaviors among opioid-dependent individuals: results from the Clinical Trials Network.
(Substance use & misuse, 2011-01)
The sample included 343 opioid-dependent adults enrolled in two national multisite
studies of the National Drug Abuse Treatment Clinical Trials Network (CTN001-002).
Opioid-dependent individuals were recruited from 12 sites ...
How do prescription opioid users differ from users of heroin or other drugs in psychopathology: results from the National Epidemiologic Survey on Alcohol and Related Conditions.
(Journal of addiction medicine, 2011-03)
To study substance use and psychiatric disorders among prescription opioid users,
heroin users, and non-opioid drug users in a national sample of adults.Analyses of
data from the 2001-2002 National Epidemiologic Survey on ...
Use of item response theory and latent class analysis to link poly-substance use disorders with addiction severity, HIV risk, and quality of life among opioid-dependent patients in the Clinical Trials Network.
(Drug and alcohol dependence, 2011-11)
BACKGROUND:This study applied item response theory (IRT) and latent class analysis
(LCA) procedures to examine the dimensionality and heterogeneity of comorbid substance
use disorders (SUDs) and explored their utility for ...
The epidemiology of alcohol use disorders and subthreshold dependence in a middle-aged and elderly community sample.
(The American journal of geriatric psychiatry : official journal of the American Association
for Geriatric Psychiatry, 2011-08)
To estimate 1-year prevalence and correlates of alcohol abuse, dependence, and subthreshold
dependence (diagnostic orphans) among middle-aged and elderly persons in the United
States.2005-2007 National Surveys on Drug Use ...
Neural correlates of emotional processing in depression: changes with cognitive behavioral therapy and predictors of treatment response.
(J Psychiatr Res, 2011-05)
Major depressive disorder (MDD) is characterized by the presence of disturbances in
emotional processing. However, the neural correlates of these alterations, and how
they may be affected by therapeutic interventions, remain ...