Search
Now showing items 1-10 of 25
A genome-wide association study of variants associated with acquisition of Staphylococcus aureus bacteremia in a healthcare setting.
(BMC Infect Dis, 2014-02-13)
BACKGROUND: Humans vary in their susceptibility to acquiring Staphylococcus aureus
infection, and research suggests that there is a genetic basis for this variability.
Several recent genome-wide association studies (GWAS) ...
Patient expectation is the most important predictor of discharge destination after primary total joint arthroplasty.
(J Arthroplasty, 2015-04)
The purpose of this study was to identify preoperative predictors of discharge destination
after total joint arthroplasty. A retrospective study of three hundred and seventy-two
consecutive patients who underwent primary ...
Genome-wide association study of perioperative myocardial infarction after coronary artery bypass surgery.
(BMJ Open, 2015-05-06)
OBJECTIVES: Identification of patient subpopulations susceptible to develop myocardial
infarction (MI) or, conversely, those displaying either intrinsic cardioprotective
phenotypes or highly responsive to protective interventions ...
A randomized Phase 2 trial of telavancin versus standard therapy in patients with uncomplicated Staphylococcus aureus bacteremia: the ASSURE study.
(BMC Infect Dis, 2014-05-23)
BACKGROUND: Staphylococcus aureus bacteremia is a common infection associated with
significant morbidity and mortality. Telavancin is a bactericidal lipoglycopeptide
active against Gram-positive pathogens, including ...
Renal systems biology of patients with systemic inflammatory response syndrome.
(Kidney Int, 2015-10)
A systems biology approach was used to comprehensively examine the impact of renal
disease and hemodialysis (HD) on patient response during critical illness. To achieve
this, we examined the metabolome, proteome, ...
Delays in appropriate antibiotic therapy for gram-negative bloodstream infections: a multicenter, community hospital study.
(PLoS One, 2013)
BACKGROUND: Gram-negative bacterial bloodstream infection (BSI) is a serious condition
with estimated 30% mortality. Clinical outcomes for patients with severe infections
improve when antibiotics are appropriately chosen ...
Host gene expression classifiers diagnose acute respiratory illness etiology.
(Sci Transl Med, 2016-01-20)
Acute respiratory infections caused by bacterial or viral pathogens are among the
most common reasons for seeking medical care. Despite improvements in pathogen-based
diagnostics, most patients receive inappropriate antibiotics. ...
Preoperative predictors of extended hospital length of stay following total knee arthroplasty.
(J Arthroplasty, 2015-03)
The purpose of this study was to identify the preoperative predictors of hospital
length of stay after primary total knee arthroplasty in a patient population reflecting
current trends toward shorter hospitalization and ...
Bacteremic disseminated tuberculosis in sub-saharan Africa: a prospective cohort study.
(Clin Infect Dis, 2012-07)
BACKGROUND: Disseminated tuberculosis is a major health problem in countries where
generalized human immunodeficiency virus (HIV) infection epidemics coincide with high
tuberculosis incidence rates; data are limited on patient ...
Polymorphisms in Fibronectin Binding Proteins A and B among Staphylococcus aureus Bloodstream Isolates Are Not Associated with Arthroplasty Infection.
(PLoS One, 2015)
BACKGROUND: Nonsynonymous single nucleotide polymorphisms (SNPs) in fibronectin binding
protein A (fnbA) of Staphylococcus aureus are associated with cardiac device infections.
However, the role of fnbA SNPs in S. aureus ...