Now showing items 1-6 of 6
Genome-wide analyses of exonic copy number variants in a family-based study point to novel autism susceptibility genes.
(PLoS Genet, 2009-06)
The genetics underlying the autism spectrum disorders (ASDs) is complex and remains poorly understood. Previous work has demonstrated an important role for structural variation in a subset of cases, but has lacked the resolution ...
Differential developmental trajectories of magnetic susceptibility in human brain gray and white matter over the lifespan.
(Hum Brain Mapp, 2014-06)
As indicated by several recent studies, magnetic susceptibility of the brain is influenced mainly by myelin in the white matter and by iron deposits in the deep nuclei. Myelination and iron deposition in the brain evolve ...
The impact of the developmental timing of trauma exposure on PTSD symptoms and psychosocial functioning among older adults.
(Dev Psychol, 2013-11)
The present study examined the impact of the developmental timing of trauma exposure on posttraumatic stress disorder (PTSD) symptoms and psychosocial functioning in a large sample of community-dwelling older adults (N = ...
Credit scores, cardiovascular disease risk, and human capital.
(Proc Natl Acad Sci U S A, 2014-12-02)
Credit scores are the most widely used instruments to assess whether or not a person is a financial risk. Credit scoring has been so successful that it has expanded beyond lending and into our everyday lives, even to inform ...
Is chronic asthma associated with shorter leukocyte telomere length at midlife?
(Am J Respir Crit Care Med, 2014-08-15)
RATIONALE: Asthma is prospectively associated with age-related chronic diseases and mortality, suggesting the hypothesis that asthma may relate to a general, multisystem phenotype of accelerated aging. OBJECTIVES: To test ...
Cardiorespiratory fitness and cognitive function in midlife: neuroprotection or neuroselection?
(Ann Neurol, 2015-04)
OBJECTIVE: A study was undertaken to determine whether better cognitive functioning at midlife among more physically fit individuals reflects neuroprotection, by which fitness protects against age-related cognitive decline, ...