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An integrated approach to the prediction of chemotherapeutic response in patients with breast cancer.
(PLoS One, 2008-04-02)
BACKGROUND: A major challenge in oncology is the selection of the most effective chemotherapeutic
agents for individual patients, while the administration of ineffective chemotherapy
increases mortality and decreases quality ...
Gene expression signatures of radiation response are specific, durable and accurate in mice and humans.
(PLoS One, 2008-04-02)
BACKGROUND: Previous work has demonstrated the potential for peripheral blood (PB)
gene expression profiling for the detection of disease or environmental exposures.
METHODS AND FINDINGS: We have sought to determine the ...
Age-specific differences in oncogenic pathway deregulation seen in human breast tumors.
(PLoS One, 2008-01-02)
PURPOSE: To define the biology driving the aggressive nature of breast cancer arising
in young women. EXPERIMENTAL DESIGN: Among 784 patients with early stage breast cancer,
using prospectively-defined, age-specific cohorts ...
Gene expression signatures of radiation response are specific, durable and accurate in mice and humans.
(PLoS One, 2008-04-02)
BACKGROUND: Previous work has demonstrated the potential for peripheral blood (PB)
gene expression profiling for the detection of disease or environmental exposures.
METHODS AND FINDINGS: We have sought to determine the ...