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An integrated approach to the prediction of chemotherapeutic response in patients with breast cancer.

Acharya, CR; Anders, CK; Anguiano, A; Barry, WT; Dressman, HK; Garman, Katherine S; Marcom, Kelly; ... (14 authors) (PLoS One, 2008-04-02)

BACKGROUND: A major challenge in oncology is the selection of the most effective chemotherapeutic agents for individual patients, while the administration of ineffective chemotherapy increases mortality and decreases quality ...

Gene expression signatures that predict radiation exposure in mice and humans.

Chao, Nelson J; Chute, JP; Dressman, HK; Ginsburg, Geoffrey Steven; Marshall, D; Meadows, Sarah K; Muramoto, Garrett G; ... (8 authors) (PLoS Med, 2007-04)

BACKGROUND: The capacity to assess environmental inputs to biological phenotypes is limited by methods that can accurately and quantitatively measure these contributions. One such example can be seen in the context of exposure ...