Now showing items 1-3 of 3
Potentially functional genetic variants in the complement-related immunity gene-set are associated with non-small cell lung cancer survival.
(International journal of cancer, 2019-04)
The complement system plays an important role in the innate and adaptive immunity, complement components mediate tumor cytolysis of antibody-based immunotherapy, and complement activation in the tumor microenvironment may ...
Genetic variants in the liver kinase B1-AMP-activated protein kinase pathway genes and pancreatic cancer risk.
(Molecular carcinogenesis, 2019-04-17)
The liver kinase B1-AMP-activated protein kinase (LKB1-AMPK) pathway has been identified as a new target for cancer therapy, because it controls the glucose and lipid metabolism in response to alterations in nutrients and ...
Genetic variants of genes in the NER pathway associated with risk of breast cancer: A large-scale analysis of 14 published GWAS datasets in the DRIVE study.
(International journal of cancer, 2019-09)
A recent hypothesis-free pathway-level analysis of genome-wide association study (GWAS) datasets suggested that the overall genetic variation measured by single nucleotide polymorphisms (SNPs) in the nucleotide excision ...