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Genotypes and haplotypes of the VEGF gene and survival in locally advanced non-small cell lung cancer patients treated with chemoradiotherapy.
(BMC cancer, 2010-08-16)
Vascular endothelial growth factor (VEGF) is a major mediator of angiogenesis involving
in carcinogenesis, including lung cancer. We hypothesized that VEGF polymorphisms
may affect survival outcomes among locally advanced ...
Rationale and design of the Exercise Intensity Trial (EXCITE): A randomized trial comparing the effects of moderate versus moderate to high-intensity aerobic training in women with operable breast cancer.
(BMC Cancer, 2010-10-06)
BACKGROUND: The Exercise Intensity Trial (EXcITe) is a randomized trial to compare
the efficacy of supervised moderate-intensity aerobic training to moderate to high-intensity
aerobic training, relative to attention control, ...
Viral factors induce Hedgehog pathway activation in humans with viral hepatitis, cirrhosis, and hepatocellular carcinoma.
(Lab Invest, 2010-12)
Hedgehog (Hh) pathway activation promotes many processes that occur during fibrogenic
liver repair. Whether the Hh pathway modulates the outcomes of virally mediated liver
injury has never been examined. Gene-profiling studies ...
Cryptococcal cell morphology affects host cell interactions and pathogenicity.
(PLoS Pathog, 2010-06-17)
Cryptococcus neoformans is a common life-threatening human fungal pathogen. The size
of cryptococcal cells is typically 5 to 10 microm. Cell enlargement was observed in
vivo, producing cells up to 100 microm. These morphological ...
Diagnosis of partial body radiation exposure in mice using peripheral blood gene expression profiles.
(PLoS One, 2010-07-12)
In the event of a terrorist-mediated attack in the United States using radiological
or improvised nuclear weapons, it is expected that hundreds of thousands of people
could be exposed to life-threatening levels of ionizing ...
Establishing a regional, multisite database for quality improvement and service planning in community-based palliative care and hospice.
(J Palliat Med, 2010-08)
BACKGROUND: Outpatient palliative care, an evolving delivery model, seeks to improve
continuity of care across settings and to increase access to services in hospice and
palliative medicine (HPM). It can provide a critical ...
Impact of gene variants on sex-specific regulation of human Scavenger receptor class B type 1 (SR-BI) expression in liver and association with lipid levels in a population-based study.
(BMC Med Genet, 2010-01-19)
BACKGROUND: Several studies have noted that genetic variants of SCARB1, a lipoprotein
receptor involved in reverse cholesterol transport, are associated with serum lipid
levels in a sex-dependent fashion. However, the mechanism ...
The lung cancer exercise training study: a randomized trial of aerobic training, resistance training, or both in postsurgical lung cancer patients: rationale and design.
(BMC Cancer, 2010-04-21)
BACKGROUND: The Lung Cancer Exercise Training Study (LUNGEVITY) is a randomized trial
to investigate the efficacy of different types of exercise training on cardiorespiratory
fitness (VO2peak), patient-reported outcomes, ...
Rationale and design of the Exercise Intensity Trial (EXCITE): A randomized trial comparing the effects of moderate versus moderate to high-intensity aerobic training in women with operable breast cancer.
(BMC Cancer, 2010-10-06)
BACKGROUND: The Exercise Intensity Trial (EXcITe) is a randomized trial to compare
the efficacy of supervised moderate-intensity aerobic training to moderate to high-intensity
aerobic training, relative to attention control, ...
Variation in use of surveillance colonoscopy among colorectal cancer survivors in the United States.
(BMC Health Serv Res, 2010-09-01)
BACKGROUND: Clinical practice guidelines recommend colonoscopies at regular intervals
for colorectal cancer (CRC) survivors. Using data from a large, multi-regional, population-based
cohort, we describe the rate of surveillance ...