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Epidermal growth factor regulates hematopoietic regeneration after radiation injury.
(Nat Med, 2013-03)
The mechanisms that regulate hematopoietic stem cell (HSC) regeneration after myelosuppressive
injury are not well understood. We identified epidermal growth factor (EGF) to be
highly enriched in the bone marrow serum of ...
Protein tyrosine phosphatase-σ regulates hematopoietic stem cell-repopulating capacity.
(J Clin Invest, 2015-01)
Hematopoietic stem cell (HSC) function is regulated by activation of receptor tyrosine
kinases (RTKs). Receptor protein tyrosine phosphatases (PTPs) counterbalance RTK signaling;
however, the functions of receptor PTPs in ...
Diagnosis of partial body radiation exposure in mice using peripheral blood gene expression profiles.
(PLoS One, 2010-07-12)
In the event of a terrorist-mediated attack in the United States using radiological
or improvised nuclear weapons, it is expected that hundreds of thousands of people
could be exposed to life-threatening levels of ionizing ...
A translatable predictor of human radiation exposure.
(PLoS One, 2014)
Terrorism using radiological dirty bombs or improvised nuclear devices is recognized
as a major threat to both public health and national security. In the event of a radiological
or nuclear disaster, rapid and accurate ...