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Now showing items 1-10 of 148

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Establishment and maintenance of a PBMC repository for functional cellular studies in support of clinical vaccine trials. 

Berrong, Mark; Brown, S; Cox, J; D'Souza, M Patricia; Denny, Thomas Norton; Ferrari, Guido; Frahm, N; ... (19 authors) (J Immunol Methods, 2014-07)
A large repository of cryopreserved peripheral blood mononuclear cells (PBMCs) samples was created to provide laboratories testing the specimens from human immunodeficiency virus-1 (HIV-1) vaccine clinical trials the material ...
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Gastroesophageal reflux symptoms are not sufficient to guide esophageal function testing in lung transplant candidates. 

Posner, S; Zheng, J; Wood, RK; Shimpi, RA; Hartwig, MG; Chow, S-C; Leiman, DA (Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2018-05)
Gastroesophageal reflux disease and esophageal dysmotility are prevalent in patients with advanced lung disease and are associated with graft dysfunction following lung transplantation. As a result, many transplant centers ...
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Potential Cost-effectiveness of Early Identification of Hospital-acquired Infection in Critically Ill Patients. 

Tsalik, Ephraim L; Li, Yanhong; Hudson, Lori L; Chu, Vivian H; Himmel, Tiffany; Limkakeng, Alex T; Katz, Jason N; ... (14 authors) (Ann Am Thorac Soc, 2016-03)
RATIONALE: Limitations in methods for the rapid diagnosis of hospital-acquired infections often delay initiation of effective antimicrobial therapy. New diagnostic approaches offer potential clinical and cost-related improvements ...
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Polymorphisms in Fibronectin Binding Proteins A and B among Staphylococcus aureus Bloodstream Isolates Are Not Associated with Arthroplasty Infection. 

Eichenberger, Emily M; Thaden, Joshua T; Sharma-Kuinkel, Batu; Park, Lawrence P; Rude, Thomas H; Ruffin, Felicia; Hos, Nina J; ... (13 authors) (PLoS One, 2015)
BACKGROUND: Nonsynonymous single nucleotide polymorphisms (SNPs) in fibronectin binding protein A (fnbA) of Staphylococcus aureus are associated with cardiac device infections. However, the role of fnbA SNPs in S. aureus ...
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Associations of PI3KR1 and mTOR polymorphisms with esophageal squamous cell carcinoma risk and gene-environment interactions in Eastern Chinese populations. 

Zhu, Jinhong; Wang, Mengyun; Zhu, Meiling; He, Jin; Wang, Jiu-Cun; Jin, Li; Wang, Xiao-Feng; ... (9 authors) (Scientific reports, 2015-01)
Single nucleotide polymorphisms (SNPs) in the PI3K/PTEN/AKT/mTOR signaling pathway may contribute to carcinogenesis. We genotyped five potentially functional PIK3R1 and mTOR SNPs in 1116 esophageal squamous cell cancer (ESCC) ...
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Steps to Health employee weight management randomized control trial: short-term follow-up results. 

Østbye, Truls; Stroo, Marissa; Brouwer, Rebecca JN; Peterson, Bercedis L; Eisenstein, Eric L; Fuemmeler, Bernard F; Joyner, Julie; ... (9 authors) (J Occup Environ Med, 2015-02)
OBJECTIVE: To present the short-term follow-up findings of the Steps to Health study, a randomized trial to evaluate the effectiveness of two employee weight management programs offered within Duke University and the Health ...
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Nurse-led behavioral management of diabetes and hypertension in community practices: a randomized trial. 

Edelman, David; Dolor, Rowena J; Coffman, Cynthia J; Pereira, Katherine C; Granger, Bradi B; Lindquist, Jennifer H; Neary, Alice M; ... (9 authors) (J Gen Intern Med, 2015-05)
BACKGROUND: Several trials have demonstrated the efficacy of nurse telephone case management for diabetes (DM) and hypertension (HTN) in academic or vertically integrated systems. Little is known about the real-world potency ...
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Persistent high serum bicarbonate and the risk of heart failure in patients with chronic kidney disease (CKD): A report from the Chronic Renal Insufficiency Cohort (CRIC) study. 

Dobre, Mirela; Yang, Wei; Pan, Qiang; Appel, Lawrence; Bellovich, Keith; Chen, Jing; Feldman, Harold; ... (17 authors) (Journal of the American Heart Association, 2015-04-20)
Serum bicarbonate varies over time in chronic kidney disease (CKD) patients, and this variability may portend poor cardiovascular outcomes. The aim of this study was to conduct a time-updated longitudinal analysis to evaluate ...
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Genome-wide association study of perioperative myocardial infarction after coronary artery bypass surgery. 

Kertai, Miklos D; Li, Yi-Ju; Li, Yen-Wei; Ji, Yunqi; Alexander, John; Newman, Mark F; Smith, Peter K; ... (11 authors) (BMJ Open, 2015-05-06)
OBJECTIVES: Identification of patient subpopulations susceptible to develop myocardial infarction (MI) or, conversely, those displaying either intrinsic cardioprotective phenotypes or highly responsive to protective interventions ...
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Renal systems biology of patients with systemic inflammatory response syndrome. 

Tsalik, Ephraim L; Willig, Laurel K; Rice, Brandon J; van Velkinburgh, Jennifer C; Mohney, Robert P; McDunn, Jonathan E; Dinwiddie, Darrell L; ... (21 authors) (Kidney Int, 2015-10)
A systems biology approach was used to comprehensively examine the impact of renal disease and hemodialysis (HD) on patient response during critical illness. To achieve this, we examined the metabolome, proteome, ...
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