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Association between single nucleotide polymorphisms in ERCC4 and risk of squamous cell carcinoma of the head and neck.
(PloS one, 2012-01)
Excision repair cross-complementation group 4 gene (ERCC4/XPF) plays an important
role in nucleotide excision repair and participates in removal of DNA interstrand
cross-links and DNA double-strand breaks. Single nucleotide ...
Are patients with longer emergency department wait times less likely to consent to research?
(Acad Emerg Med, 2012-04)
OBJECTIVES: There are unique challenges to enrolling patients in emergency department
(ED) clinical research studies, including the time-sensitive nature of emergency conditions,
the acute care environment, and the lack ...
Partial anomalous pulmonary venous connection and pulmonary arterial hypertension.
(Respirology, 2012-08)
BACKGROUND AND OBJECTIVE: Isolated partial anomalous pulmonary venous connection (PAPVC)
has been implicated as a cause of pulmonary arterial hypertension (PAH); however this
condition is often overlooked in the diagnostic ...
Bacteremic disseminated tuberculosis in sub-saharan Africa: a prospective cohort study.
(Clin Infect Dis, 2012-07)
BACKGROUND: Disseminated tuberculosis is a major health problem in countries where
generalized human immunodeficiency virus (HIV) infection epidemics coincide with high
tuberculosis incidence rates; data are limited on patient ...
Changes in HIV risk behavior and seroincidence among clients presenting for repeat HIV counseling and testing in Moshi, Tanzania.
(AIDS Care, 2012)
While HIV counseling and testing (HCT) has been considered an HIV preventive measure
in Africa, data are limited describing behavior changes following HCT. This study
evaluated behavior changes and estimated HIV seroincidence ...
Brucellosis among hospitalized febrile patients in northern Tanzania.
(Am J Trop Med Hyg, 2012-12)
Acute and convalescent serum samples were collected from febrile inpatients identified
at two hospitals in Moshi, Tanzania. Confirmed brucellosis was defined as a positive
blood culture or a ≥ 4-fold increase in ...
Age-related effects on the neural correlates of autobiographical memory retrieval.
(Neurobiol Aging, 2012-07)
Older adults recall less episodically rich autobiographical memories (AM), however,
the neural basis of this effect is not clear. Using functional MRI, we examined the
effects of age during search and elaboration phases ...
On the interplay of telomeres, nevi and the risk of melanoma.
(PloS one, 2012-01)
The relationship between telomeres, nevi and melanoma is complex. Shorter telomeres
have been found to be associated with many cancers and with number of nevi, a known
risk factor for melanoma. However, shorter telomeres ...
Detectable clonal mosaicism from birth to old age and its relationship to cancer.
(Nature genetics, 2012-05-06)
We detected clonal mosaicism for large chromosomal anomalies (duplications, deletions
and uniparental disomy) using SNP microarray data from over 50,000 subjects recruited
for genome-wide association studies. This detection ...
Tumor necrosis factor-α induced protein 8 polymorphism and risk of non-Hodgkin's lymphoma in a Chinese population: a case-control study.
(PloS one, 2012-01)
BACKGROUND: Non-Hodgkin's lymphoma (NHL) has been reported to be associated with autoimmune
and pro-inflammatory response, and genetic polymorphisms of candidate genes involved
in autoimmune and pro-inflammatory response ...