Now showing items 1-5 of 5
Statistical analysis of crystallization database links protein physico-chemical features with crystallization mechanisms.
(PLoS One, 2014)
X-ray crystallography is the predominant method for obtaining atomic-scale information about biological macromolecules. Despite the success of the technique, obtaining well diffracting crystals still critically limits going ...
Competition between monomeric and dimeric crystals in schematic models for globular proteins.
(J Phys Chem B, 2014-07-17)
Advances in experimental techniques and in theoretical models have improved our understanding of protein crystallization. However, they have also left open questions regarding the protein phase behavior and self-assembly ...
Soft matter perspective on protein crystal assembly.
(Colloids Surf B Biointerfaces, 2016-01-01)
Crystallography may be the gold standard of protein structure determination, but obtaining the necessary high-quality crystals is also in some ways akin to prospecting for the precious metal. The tools and models developed ...
Characterizing protein crystal contacts and their role in crystallization: rubredoxin as a case study.
(Soft Matter, 2014-01-14)
The fields of structural biology and soft matter have independently sought out fundamental principles to rationalize protein crystallization. Yet the conceptual differences and the limited overlap between the two disciplines ...
Crystallization of asymmetric patchy models for globular proteins in solution.
(Phys Rev E Stat Nonlin Soft Matter Phys, 2013-07)
Asymmetric patchy particle models have recently been shown to describe the crystallization of small globular proteins with near-quantitative accuracy. Here, we investigate how asymmetry in patch geometry and bond energy ...