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Associations of PI3KR1 and mTOR polymorphisms with esophageal squamous cell carcinoma risk and gene-environment interactions in Eastern Chinese populations.

Wei, Qingyi; Zhu, Jinhong; Wang, Mengyun; Zhu, Meiling; He, Jin; Wang, Jiu-Cun; Jin, Li; ... (9 authors) (Scientific reports, 2015-01)

Single nucleotide polymorphisms (SNPs) in the PI3K/PTEN/AKT/mTOR signaling pathway may contribute to carcinogenesis. We genotyped five potentially functional PIK3R1 and mTOR SNPs in 1116 esophageal squamous cell cancer (ESCC) ...

Genetic variant of PRKAA1 and gastric cancer risk in an eastern Chinese population.

Wei, Qingyi; Qiu, Li-Xin; He, Jing; Cheng, Lei; Zhou, Fei; Wang, Meng-Yun; Sun, Meng-Hong; ... (15 authors) (Oncotarget, 2015-12)

Published data on the association between PRKAA1 rs13361707 T > C polymorphism and gastric cancer (GCa) susceptibility were inconclusive. To derive a more precise estimation of the association, we conducted a large-scale ...