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Activation and targeting of extracellular signal-regulated kinases by beta-arrestin scaffolds.

Choy, EW; Field, ME; Lefkowitz, Robert J; Luttrell, LM; Miller, WE; Pierce, KL; Roudabush, FL (Proc Natl Acad Sci U S A, 2001-02-27)

Using both confocal immunofluorescence microscopy and biochemical approaches, we have examined the role of beta-arrestins in the activation and targeting of extracellular signal-regulated kinase 2 (ERK2) following stimulation ...