Now showing items 1-10 of 169
Myosin VIIA, important for human auditory function, is necessary for Drosophila auditory organ development.
(PLoS One, 2008-05-07)
BACKGROUND: Myosin VIIA (MyoVIIA) is an unconventional myosin necessary for vertebrate audition -. Human auditory transduction occurs in sensory hair cells with a staircase-like arrangement of apical protrusions called ...
Fiber type-specific nitric oxide protects oxidative myofibers against cachectic stimuli.
(PLoS One, 2008-05-07)
Oxidative skeletal muscles are more resistant than glycolytic muscles to cachexia caused by chronic heart failure and other chronic diseases. The molecular mechanism for the protection associated with oxidative phenotype ...
Toxicity of pendimethalin to nontarget soil organisms.
(Bulletin of environmental contamination and toxicology, 2005-04)
From offshore to onshore: multiple origins of shallow-water corals from deep-sea ancestors.
(PLoS One, 2008-06-18)
Shallow-water tropical reefs and the deep sea represent the two most diverse marine environments. Understanding the origin and diversification of this biodiversity is a major quest in ecology and evolution. The most prominent ...
Study in vitro and in vivo of nociceptin/orphanin FQ(1-13)NH2 analogues substituting N-Me-Gly for Gly2 or Gly3.
In the present study, two analogues containing N-Me-Gly (Sarcosine, Sar) were synthesized to further investigate the structural-activity relationships of orphanin FQ/nociceptin (OFQ/NC, NC). The replacement of Gly(2) or ...
Effects of nociceptin (13-17) in pain modulation at supraspinal level in mice.
(Neurosci Lett, 2002-10-11)
This work was designed to observe the effects of nociceptin(13-17), one of the main metabolites of nociceptin (also termed orphanin FQ), in pain modulation at supraspinal level in mice. Intracerebroventricular (i.c.v.) ...
Plants as reef fish: fitting the functional form of seedling recruitment.
(Am Nat, 2007-08)
The life histories of many species depend first on dispersal to local sites and then on establishment. After dispersal, density-independent and density-dependent mortalities modify propagule supply, determining the number ...
(Clin Orthop Relat Res, 2004-06)
The DLK-1 kinase promotes mRNA stability and local translation in C. elegans synapses and axon regeneration.
Growth cone guidance and synaptic plasticity involve dynamic local changes in proteins at axons and dendrites. The Dual-Leucine zipper Kinase MAPKKK (DLK) has been previously implicated in synaptogenesis and axon outgrowth ...
Synthetic lethal analysis of Caenorhabditis elegans posterior embryonic patterning genes identifies conserved genetic interactions.
(Genome Biol, 2005)
Phenotypic robustness is evidenced when single-gene mutations do not result in an obvious phenotype. It has been suggested that such phenotypic stability results from 'buffering' activities of homologous genes as well as ...